Anemia por deficiencia de hierro: mecanismos, tratamientos y suplementación.

Saved in:

Bibliographic Details
Title:	Anemia por deficiencia de hierro: mecanismos, tratamientos y suplementación.
Alternate Title:	Iron deficiency anemia: mechanisms, treatments and supplementation.
Authors:	Ramos Peñafiel, Christian¹, Álvarez Altamirano, Karolina², Ventura Enriquez, Yanet³, Cordero Hernández, Edgar¹, Martínez Moreno, Emmanuel¹, Olarte Carrillo, Irma⁴, Gallardo Rodríguez, Adán Germán⁵ nutriologo.agallardo8@gmail.com
Source:	Ginecología y Obstetricia de México. mar2025, Vol. 93 Issue 3, p86-102. 17p.
Subjects:	IRON deficiency anemia, CHILDBEARING age, IRON deficiency, MATERNAL mortality, QUALITY of life
Abstract (English):	BACKGROUND: Iron deficiency is the leading cause of anemia worldwide, affecting one-third of the population, especially children under 5 and women of reproductive age. Iron deficiency affects quality of life at all ages and significantly reduces years of healthy life. The prevalence varies worldwide, even among people in countries with limited access to medical care and nutritional programs. In Mexico, anemia affects 27.8% of pregnant women, with higher rates in rural areas. Maternal anemia affects neonatal health and contributes to 115,000 maternal deaths worldwide each year. OBJECTIVE: To review the main characteristics of the mechanism, treatment, and formulations associated with iron deficiency anemia. METHODOLOGY: Systematic literature search of retrospective and prospective studies in PubMed, EMBASE, and Cochrane databases from 1990 to 2024. Selection criteria included studies of patients with anemia associated with iron deficiency who received oral or liposomal treatment or other types of formulations, such as new therapeutic options. CONCLUSIONS: In recent years, new formulations based on the use of liposomes to improve absorption and reduce adverse events, especially gastrointestinal, have become available. These new formulations represent a promising option for pregnant women and older adults. [ABSTRACT FROM AUTHOR]
Abstract (Spanish):	ANTECEDENTES: La deficiencia de hierro es la principal causa de anemia en el mundo, afecta a un tercio de la población, sobre todo a niños menores de cinco años y mujeres en edad reproductiva. Esta deficiencia afecta la calidad de vida en cualquier edad y reduce, considerablemente, los años de vida saludable. La prevalencia varía, globalmente, pero aún entre los habitantes de países con acceso limitado a la atención médica y a programas de nutrición. En México, la anemia afecta al 27.8% de las mujeres embarazadas, con mayores tasas en las áreas rurales. La anemia de las madres repercute en la salud del recién nacido y, globalmente, contribuye con 115,000 muertes maternas anuales. OBJETIVO: Explorar las principales características del mecanismo, tratamiento y formulaciones asociadas con la anemia por deficiencia de hierro. METODOLOGÍA: Búsqueda sistemática de la bibliografía de estudios retrospectivos y prospectivos en las bases de datos de PubMed, EMBASE y Cochrane de 1990 a 2024. Los criterios de selección incluyeron estudios de pacientes con anemia asociada con deficiencia de hierro que recibieron tratamiento oral, liposomal o con otro tipo de formulaciones, como las nuevas opciones terapéuticas. CONCLUSIONES: En años recientes ya se dispone de nuevas formulaciones basadas en el uso de liposomas para mejorar la absorción y reducir los eventos adversos, sobre todo los gastrointestinales. Estas nuevas formulaciones representan una opción prometedora para poblaciones de mujeres embarazadas y adultos mayores. [ABSTRACT FROM AUTHOR]
	Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database:	MedicLatina

Description
Abstract:	BACKGROUND: Iron deficiency is the leading cause of anemia worldwide, affecting one-third of the population, especially children under 5 and women of reproductive age. Iron deficiency affects quality of life at all ages and significantly reduces years of healthy life. The prevalence varies worldwide, even among people in countries with limited access to medical care and nutritional programs. In Mexico, anemia affects 27.8% of pregnant women, with higher rates in rural areas. Maternal anemia affects neonatal health and contributes to 115,000 maternal deaths worldwide each year. OBJECTIVE: To review the main characteristics of the mechanism, treatment, and formulations associated with iron deficiency anemia. METHODOLOGY: Systematic literature search of retrospective and prospective studies in PubMed, EMBASE, and Cochrane databases from 1990 to 2024. Selection criteria included studies of patients with anemia associated with iron deficiency who received oral or liposomal treatment or other types of formulations, such as new therapeutic options. CONCLUSIONS: In recent years, new formulations based on the use of liposomes to improve absorption and reduce adverse events, especially gastrointestinal, have become available. These new formulations represent a promising option for pregnant women and older adults. [ABSTRACT FROM AUTHOR]
ISSN:	03009041
DOI:	10.24245/gom.v93i3.50