Bibliographic Details
| Title: |
Syndromic platforms in the management of infection in the critically ill patient: test indication and diagnostic interpretation. |
| Alternate Title: |
Plataformas sindrómicas en el manejo de infecciones en pacientes críticos: indicación de pruebas e interpretación diagnóstica. |
| Authors: |
Sanz, Sara1, Burillo, Natalia1, García-Lechuz, Juan Manuel1 jmgarcialechuz@salud.aragon.es |
| Source: |
Revista Española de Quimioterapia. 2025 Supplement, Vol. 38, p27-31. 5p. |
| Subjects: |
SEPSIS, MULTIDRUG resistance in bacteria, INFECTION control, INTENSIVE care units, ANTIBIOTICS, RAPID diagnostic tests, CRITICALLY ill patient care |
| Abstract (English): |
The timely and appropriate administration of empirical antibiotic therapy is critical for patient survival. However, several studies suggest that approximately 20-30% of patients presenting with sepsis receive inadequate antibiotic treatment, a factor strongly associated with increased mortality. Furthermore, approximately 20% of these patients experience adverse effects. The emergence of multidrug-resistant bacteria has significantly complicated the selection of appropriate antibiotic therapy and contributed to increased mortality. This challenge is particularly pronounced in conditions such as ventilator-associated pneumonia and bacteremia of various origins, which represent some of the most common infectious pathologies in the intensive care unit. This has resulted in the development of a range of rapid diagnostic tools, including syndromic panels. The primary objective of these panels is to identify the causative agent of infection at an early stage and to guide the selection of the optimal treatment as quickly as possible. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
La administración oportuna y adecuada de la terapia antimicrobiana empírica es fundamental para la supervivencia del paciente. Sin embargo, varios estudios sugieren que, aproximadamente, entre el 20% y el 30% de los pacientes que presentan sepsis reciben un tratamiento antimicrobiano inadecuado, un factor estrechamente relacionado con el aumento de la mortalidad. Además, aproximadamente el 20% de estos pacientes experimenta efectos adversos. La aparición de bacterias multirresistentes ha complicado significativamente la selección de la terapia antimicrobiana adecuada y ha contribuido al aumento de la mortalidad. Este desafío es particularmente pronunciado en infecciones como la neumonía asociada a ventilación mecánica y la bacteriemia de diversos orígenes, que representan algunas de las patologías infecciosas más comunes en la unidad de cuidados intensivos. Esto ha dado lugar al desarrollo de una serie de herramientas de diagnóstico rápido, incluidos los paneles sindrómicos. El objetivo principal de estos paneles es identificar el agente causante de la infección en una etapa temprana y orientar la selección del tratamiento óptimo lo más rápidamente posible. [ABSTRACT FROM AUTHOR] |
|
Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
MedicLatina |
