Excipientes de medicamentos. Necesarios, pero no inocuos.

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Bibliographic Details
Title: Excipientes de medicamentos. Necesarios, pero no inocuos.
Alternate Title: Drug Excipients. Necessary, but not Harmless.
Authors: López Alarcón, María Dolores mdoloresla@gmail.com, Justo Hernández, Alicia, Santos Cruz, Paula
Source: Farmacéuticos Comunitarios. 2025, Vol. 17 Issue 4, p65-80. 16p.
Subjects: DRUG side effects, MEDICATION safety, DRUG additives, PHARMACOLOGY, REFERENCE sources, CHEMICAL properties, CHILD patients, PHARMACISTS
Abstract (English): Medicines are made up of one or more active ingredients and excipients. Active ingredients have pharmacological action and cause adverse reactions to medications, but what about excipients? They are necessary to achieve the appropriate properties of the medication, but they are not always harmless and can also cause adverse reactions. In order to provide community pharmacists with quick reference material during dispensing services, thus ensuring safe use of medicines, a bibliographic review of the available literature has been carried out, focusing on the identification of possible adverse reactions associated with excipients present in medicines and vaccines in both the pediatric and adult populations. A series of reference tables have been developed indicating potentially dangerous excipients, the adverse reactions they make produce, and the precautions to be taken into account in certain pathologies or if they are intended for the pediatric population. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Los medicamentos están formados por uno o varios principios activos y excipientes. Los principios activos poseen acción farmacológica y son los que pueden producir reacciones adversas a medicamentos, pero ¿y los excipientes? Son necesarios para conseguir las adecuadas propiedades del medicamento, pero no siempre son inocuos, pudiendo producir también reacciones adversas. Con el objetivo de disponer de material de rápida consulta para los farmacéuticos comunitarios durante el servicio de dispensación, garantizando así un uso seguro de los medicamentos, se ha realizado una revisión bibliográfica de la literatura disponible, centrada en la identificación de posibles reacciones adversas asociadas a excipientes presentes en medicamentos y vacunas, tanto en la población pediátrica como adulta. Se han elaborado una serie de tablas de consulta donde se indican excipientes potencialmente peligrosos, las reacciones adversas que pueden producir y las precauciones a tener en cuenta en determinadas patologías o en caso de estar destinados a población pediátrica. [ABSTRACT FROM AUTHOR]
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Database: MedicLatina
Description
Abstract:Medicines are made up of one or more active ingredients and excipients. Active ingredients have pharmacological action and cause adverse reactions to medications, but what about excipients? They are necessary to achieve the appropriate properties of the medication, but they are not always harmless and can also cause adverse reactions. In order to provide community pharmacists with quick reference material during dispensing services, thus ensuring safe use of medicines, a bibliographic review of the available literature has been carried out, focusing on the identification of possible adverse reactions associated with excipients present in medicines and vaccines in both the pediatric and adult populations. A series of reference tables have been developed indicating potentially dangerous excipients, the adverse reactions they make produce, and the precautions to be taken into account in certain pathologies or if they are intended for the pediatric population. [ABSTRACT FROM AUTHOR]
ISSN:18858619
DOI:10.33620/fc.2173-9218.(2024).30