Archivo de docencia de patología molecular y neuroimagen.

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Bibliographic Details
Title:	Archivo de docencia de patología molecular y neuroimagen.
Alternate Title:	Molecular pathology and neuroimaging teaching files.
Authors:	Wilson, Jon¹, González-Toledo, Eduardo² ecgtoledo@gmail.com
Source:	Revista Argentina de Radiología. 2025, Vol. 89 Issue 4, p217-223. 7p.
Abstract (English):	We present the case of a 20-year-old female patient with neurological symptoms whose magnetic resonance imaging (MRI) revealed a left frontoinsular mass. Multiparametric MRI - including diffusion-weighted imaging, diffusion tensor imaging), resting-state functional MRI, and ALPS (along the perivascular space) index - suggested an IDH (isocitrate dehidrogenase) mutant, 1p/19q non-codeleted glioma. Histopathological and molecular analyses confirmed the imaging-based hypothesis. This case highlights the power of advanced MRI techniques in the preoperative molecular characterization of gliomas. [ABSTRACT FROM AUTHOR]
Abstract (Spanish):	Se presenta el caso de una paciente de 20 años con síntomas neurológicos, cuya resonancia magnética (RM) reveló una masa en la región frontoinsular izquierda. La evaluación mediante RM multiparamétrica-incluyendo secuencias de difusión, tensores de difusión, RM funcional en estado de reposo e índice ALPS (along the perivascular space)-sugirió un glioma mutado para IDH (isocitrate dehidrogenase) y sin codeleción 1p/19q. Los estudios histopatológicos y moleculares confirmaron la sospecha diagnóstica. Este caso resalta el valor de las técnicas avanzadas de RM en la caracterización molecular preoperatoria de los gliomas. [ABSTRACT FROM AUTHOR]
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Database:	MedicLatina

Description
Abstract:	We present the case of a 20-year-old female patient with neurological symptoms whose magnetic resonance imaging (MRI) revealed a left frontoinsular mass. Multiparametric MRI - including diffusion-weighted imaging, diffusion tensor imaging), resting-state functional MRI, and ALPS (along the perivascular space) index - suggested an IDH (isocitrate dehidrogenase) mutant, 1p/19q non-codeleted glioma. Histopathological and molecular analyses confirmed the imaging-based hypothesis. This case highlights the power of advanced MRI techniques in the preoperative molecular characterization of gliomas. [ABSTRACT FROM AUTHOR]
ISSN:	00487619
DOI:	10.24875/RAR.M25000058