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Guía de práctica clínica para el diagnóstico y tratamiento de la infección por Helicobacter pylori en adultos: actualización 2025.

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Title: Guía de práctica clínica para el diagnóstico y tratamiento de la infección por Helicobacter pylori en adultos: actualización 2025.
Alternate Title: Clinical Practice Guideline for the Diagnosis and Treatment of Helicobacter Pylori Infection in Adults: 2025 Update.
Authors: Otero-Regino, William Alberto1 waoteror@gmail.com, Trespalacios-Rangel, Alba Alicia2,3, Marulanda-Fernández, Hernando4,5,6, Rojas-Gualdrón, Diego Fernando7, Aponte-Martín, Diego Mauricio8, Cañadas-Garrido, Raúl Antonio9, Ibarra-Burgos, Jaime Andrés10, Linares-Ramírez, Juan David11, Concha-Mejía, Alejandro12, Sabbagh, Luis Carlos13
Source: Revista Colombiana de Gastroenterología. 2025 Supplement, Vol. 40, p3-32. 30p.
Subjects: HELICOBACTER pylori, DIAGNOSIS, THERAPEUTICS, GASTROENTEROLOGY, MEDICAL protocols, GASTRITIS
Abstract (English): Introduction: In 2015, the Colombian Association of Gastroenterology (ACG) published a clinical practice guideline (CPG) for the diagnosis and treatment of Helicobacter pylori infection in adults. In 2025, the ACG updated this guideline to reflect advances in diagnostic and therapeutic strategies, tailored to the local microbiological context and the clinical characteristics of the Colombian population. Materials and Methods: The ACG guideline committee, in collaboration with epidemiologists, updated the guidelines based on a systematic review of clinical recommendations and meta-analyses, following the GRADE methodology. This short version of the 2025 update summarizes the evidence supporting the recommendations. The full guideline is available at www.gastrocol.com. Results: The updated guideline provides recommendations on treatment indications for H. pylori eradication and prevention of associated diseases, invasive and non-invasive diagnostic methods, therapeutic alternatives across different lines of treatment and specific considerations such as high-resistance regions, penicillin allergy, and special populations. Conclusion: Accurate diagnosis and effective treatment of H. pylori infection are essential due to its role as a risk factor for chronic gastritis, peptic ulcers, gastric MALT lymphoma, and gastric adenocarcinoma. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción: en 2015, la Asociación Colombiana de Gastroenterología (ACG) publicó la guía de práctica clínica (GPC) para el diagnóstico y tratamiento de la infección por Helicobacter pylori en adultos. En 2025, la Asociación realizó el proceso de actualización de esta guía de acuerdo con la necesidad de actualización de las estrategias diagnósticas y terapéuticas, adaptadas a la realidad microbiológica local y a las características clínicas de la población. Materiales y métodos: el comité de guías de la ACG con el acompañamiento de epidemiólogos realizó la actualización con base en una revisión sistemática de recomendaciones de práctica y metaanálisis siguiendo las directrices de la metodología GRADE. En esta versión corta de la GPC-actualización 2025 se presenta un breve resumen de la evidencia que apoya las recomendaciones. El detalle del proceso de actualización puede consultarse en la versión completa disponible en www.gastrocol.com. Resultados: la actualización de 2025 presenta recomendaciones sobre indicaciones de tratamiento para curar el H. pylori y prevenir otras patologías, métodos diagnósticos invasivos y no invasivos, alternativas de tratamiento en las diferentes líneas y consideraciones particulares como zonas de alta resistencia, alergia a la penicilina y poblaciones especiales. Conclusión: un adecuado diagnóstico y tratamiento de la infección por H. pylori es esencial dado su rol como factor de riesgo en condiciones como gastritis crónica, úlceras pépticas, linfoma MALT gástrico y adenocarcinoma del estómago. [ABSTRACT FROM AUTHOR]
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Database: MedicLatina
Description
Abstract:Introduction: In 2015, the Colombian Association of Gastroenterology (ACG) published a clinical practice guideline (CPG) for the diagnosis and treatment of Helicobacter pylori infection in adults. In 2025, the ACG updated this guideline to reflect advances in diagnostic and therapeutic strategies, tailored to the local microbiological context and the clinical characteristics of the Colombian population. Materials and Methods: The ACG guideline committee, in collaboration with epidemiologists, updated the guidelines based on a systematic review of clinical recommendations and meta-analyses, following the GRADE methodology. This short version of the 2025 update summarizes the evidence supporting the recommendations. The full guideline is available at www.gastrocol.com. Results: The updated guideline provides recommendations on treatment indications for H. pylori eradication and prevention of associated diseases, invasive and non-invasive diagnostic methods, therapeutic alternatives across different lines of treatment and specific considerations such as high-resistance regions, penicillin allergy, and special populations. Conclusion: Accurate diagnosis and effective treatment of H. pylori infection are essential due to its role as a risk factor for chronic gastritis, peptic ulcers, gastric MALT lymphoma, and gastric adenocarcinoma. [ABSTRACT FROM AUTHOR]
ISSN:01209957
DOI:10.22516/25007440.1458