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Guía de práctica clínica para el diagnóstico y tratamiento de la enfermedad por reflujo gastroesofágico (ERGE) en adultos: actualización 2025.

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Title: Guía de práctica clínica para el diagnóstico y tratamiento de la enfermedad por reflujo gastroesofágico (ERGE) en adultos: actualización 2025.
Alternate Title: Clinical Practice Guideline for the Diagnosis and Treatment of Gastroesophageal Reflux Disease (GERD) in Adults: 2025 Update.
Authors: Hani de Ardila, Albis Cecilia1 albishani@gmail.com, Antonio Cañadas-Garrido, Raúl2, Mauricio Aponte-Martín, Diego3, Ximena Ortiz-Chamorro, Angie4, Bareño-Silva, José5, Andrés Ibarra-Burgos, Jaime6, Carolina Ardila-Hani, María7, David Linares-Ramírez, Juan8, Alberto Otero-Regino, William9, Concha-Mejía, Alejandro10, Carlos Sabbagh, Luis11
Source: Revista Colombiana de Gastroenterología. 2025 Supplement, Vol. 40, p3-31. 29p.
Subjects: GASTROESOPHAGEAL reflux, DIAGNOSIS, THERAPEUTICS, MEDICAL care, MEDICAL protocols
Geographic Terms: COLOMBIA
Abstract (English): Objective: To provide an evidence-based clinical practice guideline for the diagnosis and treatment of gastroesophageal reflux disease (GERD), addressing the effectiveness and safety of interventions, and aimed at healthcare professionals managing gastrointestinal disorders in any clinical setting in Colombia. Materials and Methods: This guideline was developed by a multidisciplinary team with support from the Colombian Association of Gastroenterology and Universidad CES. Relevant clinical questions were formulated, and searches were conducted in databases of national and international guidelines. The retrieved guidelines were assessed for quality and applicability; five met criteria for adoption or adaptation. Additional evidence-based documents were considered during drafting. The Universidad CES research group performed a systematic literature review. The GRADE methodology and Evidence-to-Decision (EtD) frameworks were applied, based on guidelines, systematic reviews, and meta-analyses published between 2015 and 2025. Consensus was reached through a multidisciplinary panel, considering applicability, resource availability, and equity within the Colombian healthcare system. The complete methodology and technical appendices are available in the full version at www.gastrocol.com. Results: A clinical practice guideline was developed for the diagnosis and management of patients with GERD in Colombia, addressing six core clinical questions, with 39 evidence-based recommendations and 18 good practice points. Previous evidence was updated, new recommendations on diagnosis and management were added, and a section dedicated to pregnant patients was included. Conclusions: This update incorporates new recommendations and establishes a quality standard for the timely diagnosis and management of GERD, contributing to the reduction of disease burden and offering clear criteria for diagnostic evaluation, treatment, and follow-up. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Objetivo: brindar una guía de práctica clínica basada en la evidencia más reciente para el diagnóstico y tratamiento del reflujo gastroesofágico, considerando la efectividad y seguridad de las intervenciones, dirigida a profesionales de salud que atienden patologías gastrointestinales en cualquier servicio en Colombia. Materiales y métodos: guía desarrollada por un equipo multidisciplinario con el apoyo de la Asociación Colombiana de Gastroenterología y la Universidad CES. Se formularon preguntas clínicas relevantes y se realizó una búsqueda en bases de datos de guías nacionales e internacionales. Las guías se evaluaron en cuanto a su calidad y aplicabilidad, de las cuales cinco cumplieron criterios para adopción o adaptación. Además, se consideraron documentos basados en la evidencia para la redacción. El Grupo de la Universidad CES realizó la búsqueda sistemática de la literatura. Se empleó la metodología GRADE y marcos de evidencia a decisión (EtD) a partir de guías, revisiones sistemáticas y metaanálisis publicados entre 2015 y 2025. El consenso se alcanzó mediante un panel multidisciplinario, considerando aplicabilidad, recursos y equidad en el sistema de salud colombiano. La metodología completa y anexos técnicos están disponibles en la versión larga, disponible en www.gastrocol.com. Resultados: se desarrolló una guía de práctica clínica para el diagnóstico y tratamiento de pacientes con reflujo gastroesofágico en Colombia, con 6 preguntas centrales, 39 recomendaciones basadas en la evidencia y 18 puntos de buena práctica. Se actualizó la evidencia previa, se añadieron nuevas recomendaciones sobre el diagnóstico y manejo, y se incluyó un apartado para la población gestante. Conclusiones: esta actualización incorpora nuevas recomendaciones y establece un estándar de calidad para el diagnóstico y manejo oportunos de pacientes con ERGE, lo que contribuye a disminuir la carga de la enfermedad y ofrece criterios claros para el abordaje diagnóstico, tratamiento y seguimiento. [ABSTRACT FROM AUTHOR]
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Database: MedicLatina
Description
Abstract:Objective: To provide an evidence-based clinical practice guideline for the diagnosis and treatment of gastroesophageal reflux disease (GERD), addressing the effectiveness and safety of interventions, and aimed at healthcare professionals managing gastrointestinal disorders in any clinical setting in Colombia. Materials and Methods: This guideline was developed by a multidisciplinary team with support from the Colombian Association of Gastroenterology and Universidad CES. Relevant clinical questions were formulated, and searches were conducted in databases of national and international guidelines. The retrieved guidelines were assessed for quality and applicability; five met criteria for adoption or adaptation. Additional evidence-based documents were considered during drafting. The Universidad CES research group performed a systematic literature review. The GRADE methodology and Evidence-to-Decision (EtD) frameworks were applied, based on guidelines, systematic reviews, and meta-analyses published between 2015 and 2025. Consensus was reached through a multidisciplinary panel, considering applicability, resource availability, and equity within the Colombian healthcare system. The complete methodology and technical appendices are available in the full version at www.gastrocol.com. Results: A clinical practice guideline was developed for the diagnosis and management of patients with GERD in Colombia, addressing six core clinical questions, with 39 evidence-based recommendations and 18 good practice points. Previous evidence was updated, new recommendations on diagnosis and management were added, and a section dedicated to pregnant patients was included. Conclusions: This update incorporates new recommendations and establishes a quality standard for the timely diagnosis and management of GERD, contributing to the reduction of disease burden and offering clear criteria for diagnostic evaluation, treatment, and follow-up. [ABSTRACT FROM AUTHOR]
ISSN:01209957
DOI:10.22516/25007440.1450