Enhancing chronic kidney disease care through risk prediction: A review of the kidney failure risk equation.

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Bibliographic Details
Title: Enhancing chronic kidney disease care through risk prediction: A review of the kidney failure risk equation.
Alternate Title: Optimización de la atención de la enfermedad renal crónica mediante la predicción del riesgo: revisión de la kidney failure risk equation.
Authors: da Silva, Bernardo Marques1,2 bmsilva@campus.ul.pt, Silveira, Inês2, Lopes, José António1,2, Gameiro, Joana1,2
Source: Nefrologia. Mar2026, Vol. 46 Issue 3, p1-8. 8p.
Subjects: RISK assessment, DISEASE progression, NEPHROLOGY, DISEASE risk factors, CHRONIC kidney failure
Abstract (English): Chronic kidney disease (CKD) is a growing global health problem, with projections indicating a significant increase in its prevalence. The kidney failure risk equation (KFRE) has emerged as a valuable predictive tool to assess the risk of kidney failure in patients with CKD stages 3-5. This narrative review presents a comprehensive analysis of the KFRE's development, validation, and clinical applications, and highlights its role in predicting disease progression, guiding nephrology referrals, and planning vascular access creation. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): La enfermedad renal crónica (ERC) constituye un problema de salud global en aumento, con proyecciones que indican un incremento significativo en su prevalencia. La Kidney Failure Risk Equation (KFRE) ha surgido como una herramienta predictive valiosa para evaluar el riesgo de insuficiencia renal en pacientes con ERC en estadios 3 a 5. Esta revisión narrativa presenta un análisis exhaustivo sobre el desarrollo, validación y aplicaciones clínicas de la KFRE, y resalta su papel en la predicción de la progresión de la enfermedad, la orientación de las derivaciones a nefrología y la planificación de la creación de accesos vasculares. [ABSTRACT FROM AUTHOR]
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Database: MedicLatina
Description
Abstract:Chronic kidney disease (CKD) is a growing global health problem, with projections indicating a significant increase in its prevalence. The kidney failure risk equation (KFRE) has emerged as a valuable predictive tool to assess the risk of kidney failure in patients with CKD stages 3-5. This narrative review presents a comprehensive analysis of the KFRE's development, validation, and clinical applications, and highlights its role in predicting disease progression, guiding nephrology referrals, and planning vascular access creation. [ABSTRACT FROM AUTHOR]
ISSN:02116995
DOI:10.1016/j.nefro.2025.501473