Global incidence of chlamydia infection and HIV pre-exposure prophylaxis.
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| Title: | Global incidence of chlamydia infection and HIV pre-exposure prophylaxis. |
|---|---|
| Authors: | Zhou, Xiaoyu1 (AUTHOR), Wan, Liping2 (AUTHOR), Chen, Dandi1 (AUTHOR) cdd13880133906@outlook.com, Huang, Lihua2 (AUTHOR) |
| Source: | AIDS Reviews. Jan-Mar2026, Vol. 28 Issue 1, p21-29. 9p. |
| Subjects: | CHLAMYDIA infections, PRE-exposure prophylaxis, HIV, SEXUALLY transmitted diseases, MEN who have sex with men, EPIDEMIOLOGY, DISEASE incidence |
| Abstract: | AIDS is associated with multiple kinds of sexually transmitted infections, including chlamydia. The global epidemiological status of chlamydia infection in individuals receiving AIDS pre-exposure prophylaxis can provide the crucial information. The researchers performed an updated systematic review and meta-analysis of the case-control studies or observational studies of chlamydia infection incidence in subjects receiving AIDS pre-exposure prophylaxis of the studies after 2018. A total of 24 studies, including 67810 subjects receiving AIDS pre-exposure prophylaxis, were included in the meta-analysis. The pooled incidence of chlamydia infection before receiving AIDS pre-exposure prophylaxis in the whole population of the 24 included studies was 46.9% (p < 0.001). After at least 6 months of pre-exposure prophylaxis, the pooled incidence of chlamydia infection was 51.8% (p < 0.001). For the men who have sex with men subgroup of subjects, the pooled incidence of pre-enrollment and post-pre-exposure prophylaxis was 47.9% and 53.1%, respectively (p < 0.001). Significant heterogeneity might influence the interpretations of the meta-analysis results. Chlamydia infection incidence seems to become higher after the implementation of pre-exposure prophylaxis. In addition, the men who have sex with men subgroup are associated with the higher incidence of chlamydia infection in the pre-enrollment and post-pre-exposure prophylaxis phases. [ABSTRACT FROM AUTHOR] |
| Copyright of AIDS Reviews is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
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| Header | DbId: lth DbLabel: MedicLatina An: 192667541 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Global incidence of chlamydia infection and HIV pre-exposure prophylaxis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Zhou%2C+Xiaoyu%22">Zhou, Xiaoyu</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wan%2C+Liping%22">Wan, Liping</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Dandi%22">Chen, Dandi</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> cdd13880133906@outlook.com</i><br /><searchLink fieldCode="AR" term="%22Huang%2C+Lihua%22">Huang, Lihua</searchLink><relatesTo>2</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22AIDS+Reviews%22">AIDS Reviews</searchLink>. Jan-Mar2026, Vol. 28 Issue 1, p21-29. 9p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22CHLAMYDIA+infections%22">CHLAMYDIA infections</searchLink><br /><searchLink fieldCode="DE" term="%22PRE-exposure+prophylaxis%22">PRE-exposure prophylaxis</searchLink><br /><searchLink fieldCode="DE" term="%22HIV%22">HIV</searchLink><br /><searchLink fieldCode="DE" term="%22SEXUALLY+transmitted+diseases%22">SEXUALLY transmitted diseases</searchLink><br /><searchLink fieldCode="DE" term="%22MEN+who+have+sex+with+men%22">MEN who have sex with men</searchLink><br /><searchLink fieldCode="DE" term="%22EPIDEMIOLOGY%22">EPIDEMIOLOGY</searchLink><br /><searchLink fieldCode="DE" term="%22DISEASE+incidence%22">DISEASE incidence</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: AIDS is associated with multiple kinds of sexually transmitted infections, including chlamydia. The global epidemiological status of chlamydia infection in individuals receiving AIDS pre-exposure prophylaxis can provide the crucial information. The researchers performed an updated systematic review and meta-analysis of the case-control studies or observational studies of chlamydia infection incidence in subjects receiving AIDS pre-exposure prophylaxis of the studies after 2018. A total of 24 studies, including 67810 subjects receiving AIDS pre-exposure prophylaxis, were included in the meta-analysis. The pooled incidence of chlamydia infection before receiving AIDS pre-exposure prophylaxis in the whole population of the 24 included studies was 46.9% (p < 0.001). After at least 6 months of pre-exposure prophylaxis, the pooled incidence of chlamydia infection was 51.8% (p < 0.001). For the men who have sex with men subgroup of subjects, the pooled incidence of pre-enrollment and post-pre-exposure prophylaxis was 47.9% and 53.1%, respectively (p < 0.001). Significant heterogeneity might influence the interpretations of the meta-analysis results. Chlamydia infection incidence seems to become higher after the implementation of pre-exposure prophylaxis. In addition, the men who have sex with men subgroup are associated with the higher incidence of chlamydia infection in the pre-enrollment and post-pre-exposure prophylaxis phases. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of AIDS Reviews is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=192667541 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.24875/AIDSRev.25000026 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 9 StartPage: 21 Subjects: – SubjectFull: CHLAMYDIA infections Type: general – SubjectFull: PRE-exposure prophylaxis Type: general – SubjectFull: HIV Type: general – SubjectFull: SEXUALLY transmitted diseases Type: general – SubjectFull: MEN who have sex with men Type: general – SubjectFull: EPIDEMIOLOGY Type: general – SubjectFull: DISEASE incidence Type: general Titles: – TitleFull: Global incidence of chlamydia infection and HIV pre-exposure prophylaxis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhou, Xiaoyu – PersonEntity: Name: NameFull: Wan, Liping – PersonEntity: Name: NameFull: Chen, Dandi – PersonEntity: Name: NameFull: Huang, Lihua IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan-Mar2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 11396121 Numbering: – Type: volume Value: 28 – Type: issue Value: 1 Titles: – TitleFull: AIDS Reviews Type: main |
| ResultId | 1 |