Global incidence of chlamydia infection and HIV pre-exposure prophylaxis.

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Title: Global incidence of chlamydia infection and HIV pre-exposure prophylaxis.
Authors: Zhou, Xiaoyu1 (AUTHOR), Wan, Liping2 (AUTHOR), Chen, Dandi1 (AUTHOR) cdd13880133906@outlook.com, Huang, Lihua2 (AUTHOR)
Source: AIDS Reviews. Jan-Mar2026, Vol. 28 Issue 1, p21-29. 9p.
Subjects: CHLAMYDIA infections, PRE-exposure prophylaxis, HIV, SEXUALLY transmitted diseases, MEN who have sex with men, EPIDEMIOLOGY, DISEASE incidence
Abstract: AIDS is associated with multiple kinds of sexually transmitted infections, including chlamydia. The global epidemiological status of chlamydia infection in individuals receiving AIDS pre-exposure prophylaxis can provide the crucial information. The researchers performed an updated systematic review and meta-analysis of the case-control studies or observational studies of chlamydia infection incidence in subjects receiving AIDS pre-exposure prophylaxis of the studies after 2018. A total of 24 studies, including 67810 subjects receiving AIDS pre-exposure prophylaxis, were included in the meta-analysis. The pooled incidence of chlamydia infection before receiving AIDS pre-exposure prophylaxis in the whole population of the 24 included studies was 46.9% (p < 0.001). After at least 6 months of pre-exposure prophylaxis, the pooled incidence of chlamydia infection was 51.8% (p < 0.001). For the men who have sex with men subgroup of subjects, the pooled incidence of pre-enrollment and post-pre-exposure prophylaxis was 47.9% and 53.1%, respectively (p < 0.001). Significant heterogeneity might influence the interpretations of the meta-analysis results. Chlamydia infection incidence seems to become higher after the implementation of pre-exposure prophylaxis. In addition, the men who have sex with men subgroup are associated with the higher incidence of chlamydia infection in the pre-enrollment and post-pre-exposure prophylaxis phases. [ABSTRACT FROM AUTHOR]
Copyright of AIDS Reviews is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Global incidence of chlamydia infection and HIV pre-exposure prophylaxis.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Zhou%2C+Xiaoyu%22&quot;&gt;Zhou, Xiaoyu&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Wan%2C+Liping%22&quot;&gt;Wan, Liping&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Chen%2C+Dandi%22&quot;&gt;Chen, Dandi&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;i&gt; cdd13880133906@outlook.com&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Huang%2C+Lihua%22&quot;&gt;Huang, Lihua&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt; (AUTHOR)
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  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22AIDS+Reviews%22&quot;&gt;AIDS Reviews&lt;/searchLink&gt;. Jan-Mar2026, Vol. 28 Issue 1, p21-29. 9p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22CHLAMYDIA+infections%22&quot;&gt;CHLAMYDIA infections&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22PRE-exposure+prophylaxis%22&quot;&gt;PRE-exposure prophylaxis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22HIV%22&quot;&gt;HIV&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22SEXUALLY+transmitted+diseases%22&quot;&gt;SEXUALLY transmitted diseases&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22MEN+who+have+sex+with+men%22&quot;&gt;MEN who have sex with men&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22EPIDEMIOLOGY%22&quot;&gt;EPIDEMIOLOGY&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22DISEASE+incidence%22&quot;&gt;DISEASE incidence&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: AIDS is associated with multiple kinds of sexually transmitted infections, including chlamydia. The global epidemiological status of chlamydia infection in individuals receiving AIDS pre-exposure prophylaxis can provide the crucial information. The researchers performed an updated systematic review and meta-analysis of the case-control studies or observational studies of chlamydia infection incidence in subjects receiving AIDS pre-exposure prophylaxis of the studies after 2018. A total of 24 studies, including 67810 subjects receiving AIDS pre-exposure prophylaxis, were included in the meta-analysis. The pooled incidence of chlamydia infection before receiving AIDS pre-exposure prophylaxis in the whole population of the 24 included studies was 46.9% (p &lt; 0.001). After at least 6 months of pre-exposure prophylaxis, the pooled incidence of chlamydia infection was 51.8% (p &lt; 0.001). For the men who have sex with men subgroup of subjects, the pooled incidence of pre-enrollment and post-pre-exposure prophylaxis was 47.9% and 53.1%, respectively (p &lt; 0.001). Significant heterogeneity might influence the interpretations of the meta-analysis results. Chlamydia infection incidence seems to become higher after the implementation of pre-exposure prophylaxis. In addition, the men who have sex with men subgroup are associated with the higher incidence of chlamydia infection in the pre-enrollment and post-pre-exposure prophylaxis phases. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of AIDS Reviews is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.24875/AIDSRev.25000026
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 9
        StartPage: 21
    Subjects:
      – SubjectFull: CHLAMYDIA infections
        Type: general
      – SubjectFull: PRE-exposure prophylaxis
        Type: general
      – SubjectFull: HIV
        Type: general
      – SubjectFull: SEXUALLY transmitted diseases
        Type: general
      – SubjectFull: MEN who have sex with men
        Type: general
      – SubjectFull: EPIDEMIOLOGY
        Type: general
      – SubjectFull: DISEASE incidence
        Type: general
    Titles:
      – TitleFull: Global incidence of chlamydia infection and HIV pre-exposure prophylaxis.
        Type: main
  BibRelationships:
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      – PersonEntity:
          Name:
            NameFull: Zhou, Xiaoyu
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          Name:
            NameFull: Wan, Liping
      – PersonEntity:
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            NameFull: Chen, Dandi
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            NameFull: Huang, Lihua
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          Dates:
            – D: 01
              M: 01
              Text: Jan-Mar2026
              Type: published
              Y: 2026
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            – Type: issn-print
              Value: 11396121
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              Value: 28
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: AIDS Reviews
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