Prevención de hipoparatiroidismo con verde de indocianina en tiroidectomía transoral: estudio piloto.

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Bibliographic Details
Title:	Prevención de hipoparatiroidismo con verde de indocianina en tiroidectomía transoral: estudio piloto.
Alternate Title:	Prevention of hypoparathyroidism with indocyanine green in transoral thyroidectomy: Pilot study.
Authors:	Domínguez-Rangel, Jorge Armando¹ jorarm28@hotmail.com, Saucedo-Moreno, Eric Misael², Piscil-Salazar, Marco Antonio²
Source:	Revista Medica del IMSS. may/jun2026, Vol. 64 Issue 3, p1-8. 8p.
Subjects:	HYPOPARATHYROIDISM, THYROIDECTOMY, PARATHYROID hormone, FLUORESCENT dyes, SURGICAL complications, PARATHYROID glands, PILOT projects, CALCIUM in the body
Abstract (English):	Background: The prevalence of hypoparathyroidism following thyroidectomy is estimated to range from 15%, with a higher incidence observed in transoral endoscopic thyroidectomy via vestibular approach (TOETVA). Objective: To describe the impact of intraoperative use of indocyanine green (ICG) to identify parathyroid glands in reducing postoperative hypoparathyroidism. Material and methods: A pilot, observational, comparative, longitudinal, and ambispective study was conducted in a cohort of 55 patients who underwent laparoscopic thyroidectomy via TOETVA. Calcium (Ca) and parathyroid hormone (PTH) levels were compared immediately and 24 hours after surgery. Results: The mean age was 43.07 years (standard deviation ± 10.15). The average surgery time was 99.15 minutes (± 20.02), and the mean blood loss was 9.3 mL (± 15.9). The prevalence of biochemical postoperative hypoparathyroidism (PTH < 12 pg/mL) was 5.54%. Biochemical hypocalcemia occurred in 19 patients (34.5%), and 4 patients (7.3%) experienced clinical hypocalcemia with paresthesia. Patients were divided into 2 groups: with and without the use of ICG. No significant differences were found in the incidence of hypocalcemia or hypoparathyroidism between the 2 groups (p = 0.360 and p = 1.000, respectively). Conclusion: No differences were found in surgery time, blood loss, clinical hypocalcemia, or postoperative calcium and PTH levels. [ABSTRACT FROM AUTHOR]
Abstract (Spanish):	Introducción: la prevalencia de hipoparatiroidismo posterior a una tiroidectomía se estima en un 15% de los casos, con una mayor incidencia en tiroidectomía endoscópica transoral por vía vestibular (TOETVA). Objetivo: describir el impacto del uso transoperatorio de verde de indocianina para identificar las glándulas paratiroides en la reducción del hipoparatiroidismo posquirúrgico. Material y métodos: se realizó un estudio piloto, observacional, comparativo, longitudinal y ambispectivo en una cohorte de 55 pacientes sometidos a tiroidectomía laparoscópica tipo TOETVA. Se compararon los niveles de calcio (Ca) y hormona paratiroidea (PTH) inmediatamente después de cirugía y 24 horas después. Resultados: la edad media fue de 43.07 años (desviación estándar ± 10.15). El tiempo quirúrgico promedio fue de 99.15 minutos (± 20.02) y la pérdida sanguínea media de 9.3 mL (± 15.9). La prevalencia de hipoparatiroidismo bioquímico postoperatorio (PTH < 12 pg/mL) fue 5.54%. Se presentaron 19 pacientes con hipocalcemia bioquímica (34.5%) y 4 de hipocalcemia clínica con parestesias (7.3%). Los pacientes se dividieron en 2 grupos: con y sin uso de verde de indocianina. Al comparar ambos, no se identificaron diferencias significativas en la incidencia de hipocalcemia ni de hipoparatiroidismo (p = 0.360 y p = 1.000, respectivamente). Conclusión: no se encontraron diferencias en el tiempo quirúrgico, el sangrado, la hipocalcemia clínica ni en los niveles postoperatorios de Ca y PTH. [ABSTRACT FROM AUTHOR]
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Database:	MedicLatina

Description
Abstract:	Background: The prevalence of hypoparathyroidism following thyroidectomy is estimated to range from 15%, with a higher incidence observed in transoral endoscopic thyroidectomy via vestibular approach (TOETVA). Objective: To describe the impact of intraoperative use of indocyanine green (ICG) to identify parathyroid glands in reducing postoperative hypoparathyroidism. Material and methods: A pilot, observational, comparative, longitudinal, and ambispective study was conducted in a cohort of 55 patients who underwent laparoscopic thyroidectomy via TOETVA. Calcium (Ca) and parathyroid hormone (PTH) levels were compared immediately and 24 hours after surgery. Results: The mean age was 43.07 years (standard deviation ± 10.15). The average surgery time was 99.15 minutes (± 20.02), and the mean blood loss was 9.3 mL (± 15.9). The prevalence of biochemical postoperative hypoparathyroidism (PTH < 12 pg/mL) was 5.54%. Biochemical hypocalcemia occurred in 19 patients (34.5%), and 4 patients (7.3%) experienced clinical hypocalcemia with paresthesia. Patients were divided into 2 groups: with and without the use of ICG. No significant differences were found in the incidence of hypocalcemia or hypoparathyroidism between the 2 groups (p = 0.360 and p = 1.000, respectively). Conclusion: No differences were found in surgery time, blood loss, clinical hypocalcemia, or postoperative calcium and PTH levels. [ABSTRACT FROM AUTHOR]
ISSN:	04435117
DOI:	10.5281/zenodo.18715336