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Efectividad antimicrobiana del hipoclorito de sodio como irrigante en los tratamientos de endodoncia: revisión sistemática.

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Title: Efectividad antimicrobiana del hipoclorito de sodio como irrigante en los tratamientos de endodoncia: revisión sistemática.
Alternate Title: Antimicrobial effectiveness of sodium hypochlorite as an irrigant in endodontic treatments: A systematic review.
Authors: Jesús Salazar-Orozco, Braulio1, Cristhinee Sánchez-González, Hannia Siret1, Ramírez-Herrera, David1, Josefina Ayala-Sardúa, María2 mjayala@enes.unam.mx
Source: Revista Oral. ene-abr2026, Vol. 27 Issue 83, p2537-2546. 10p.
Subjects: SODIUM hypochlorite, IRRIGATION (Medicine), IN vitro studies, CYTOTOXINS, TREATMENT effectiveness, ENDODONTICS
Abstract (English): Introduction. The elimination of microorganisms within root canals is crucial for the success of endodontic treatment. Sodium hypochlorite (NaOCl) is currently the most widely used irrigant in root canal therapy due to its high antimicrobial capacity; however, other irrigants alternative with the same antimicrobial effectiveness have been sought. Objective. To investigate the effectiveness of NaOCl compared to other irrigants used in endodontics by searching for scientific information and to learn about other types of irrigants used in endodontics. Methodology. A systematic review was conducted under the guidelines of the PRISMA protocol, as well as the GRADE scale to determine the methodological quality of the articles. Information was collected from seven in vitro studies in three databases: PubMed, ScienceDirect and Google Scholar, considering articles published between 2019 to 2024. Results. A total of 406 articles were obtained from the database search. With the help of filters, 127 articles were selected, 43 of which were related to in vitro studies, of which 36 were examined and excluded because they did not meet the eligibility criteria. In total, seven articles that satisfactorily met the inclusion criteria were included. Conclusions. Based on the data extracted from the different in vitro studies, it is concluded that NaOCl is the irrigant with the best antimicrobial efficacy in infected root canals. Although its efficacy is recognized, caution is advised regarding its cytotoxicity at high concentrations or prolonged exposures. Compared to other agents, NaOCl is equally effective in disinfecting canals, but the choice of irrigant must take into account its specific properties and patient safe ty. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción. La eliminación de microorganismos dentro de los conductos radiculares es crucial para el éxito del tratamiento de endodoncia. Actualmente, el hipoclorito de sodio (NaClO) es el irrigador más utilizado en la terapia de conductos radiculares debido a su gran capacidad antimicrobiana; sin embargo, se han buscado otras alternativas de irrigadores con la misma efectividad. Objetivo. Investigar la efectividad del NaClO en comparación con otros irrigadores empleados en la endodoncia, mediante la búsqueda de información científica, y conocer otros tipos de irrigadores utilizados en endodoncia. Metodología. Se llevó a cabo una revisión sistemática bajo los lineamientos del protocolo PRISMA, así como de la escala GRADE, para determinar la calidad metodológica de los artículos. Se recopiló información de siete estudios in vitro en tres bases de datos: PubMed, ScienceDirect y Google Scholar, teniendo en cuenta artículos publicados entre 2019 y 2024. Resultados. De la búsqueda en las bases de datos se obtuvieron 406 artículos en total. Con la ayuda de filtros, se seleccionaron 127, 43 de estos se relacionaron con estudios in vitro, de los que se examinaron y excluyeron 36, ya que no cumplían con los criterios de elegibilidad. En total, se integraron siete artículos que cumplieron satisfactoriamente con los criterios de inclusión. Conclusiones. Con base en los datos extraídos de los diferentes estudios in vitro, se concluye que el NaClO es el irrigador que presenta mejor eficacia antimicrobiana en los conductos radiculares infectados. Aunque se reconoce su eficacia, se alerta sobre su citotoxicidad en altas concentraciones o exposiciones prolongadas. En comparación con otros agentes, el NaClO es igualmente eficaz para desinfectar los canales, pero la elección del irrigante debe tener en cuenta sus propiedades específicas y la seguridad del paciente. [ABSTRACT FROM AUTHOR]
Copyright of Revista Oral is the property of Benemerita Universidad Autonoma de Puebla and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
Description
Abstract:Introduction. The elimination of microorganisms within root canals is crucial for the success of endodontic treatment. Sodium hypochlorite (NaOCl) is currently the most widely used irrigant in root canal therapy due to its high antimicrobial capacity; however, other irrigants alternative with the same antimicrobial effectiveness have been sought. Objective. To investigate the effectiveness of NaOCl compared to other irrigants used in endodontics by searching for scientific information and to learn about other types of irrigants used in endodontics. Methodology. A systematic review was conducted under the guidelines of the PRISMA protocol, as well as the GRADE scale to determine the methodological quality of the articles. Information was collected from seven in vitro studies in three databases: PubMed, ScienceDirect and Google Scholar, considering articles published between 2019 to 2024. Results. A total of 406 articles were obtained from the database search. With the help of filters, 127 articles were selected, 43 of which were related to in vitro studies, of which 36 were examined and excluded because they did not meet the eligibility criteria. In total, seven articles that satisfactorily met the inclusion criteria were included. Conclusions. Based on the data extracted from the different in vitro studies, it is concluded that NaOCl is the irrigant with the best antimicrobial efficacy in infected root canals. Although its efficacy is recognized, caution is advised regarding its cytotoxicity at high concentrations or prolonged exposures. Compared to other agents, NaOCl is equally effective in disinfecting canals, but the choice of irrigant must take into account its specific properties and patient safe ty. [ABSTRACT FROM AUTHOR]
ISSN:1665143X