RÉPLICA A LA CARTA AL EDITOR: "EL ENDOTELIO COMO ÓRGANO: ENTRE LA METÁFORA FUNCIONAL Y LA REALIDAD ANATÓMICA".

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Bibliographic Details
Title: RÉPLICA A LA CARTA AL EDITOR: "EL ENDOTELIO COMO ÓRGANO: ENTRE LA METÁFORA FUNCIONAL Y LA REALIDAD ANATÓMICA".
Alternate Title: Response to the Letter to the Editor: "The Endothelium as an Organ: Between Functional Metaphor and Anatomical Reality".
Authors: González-Villalva, Adriana E.1
Source: Revista de la Facultad de Medicina de la UNAM. may/jun2026, Vol. 69 Issue 3, p65-66. 2p.
Subjects: ENDOTHELIUM, ORGANS (Anatomy), PATHOLOGICAL physiology, PHYSIOLOGY, INFLAMMATION, THROMBOSIS, TISSUES, ENDOTHELIAL cells
Abstract (English): The article focuses on the debate about whether the endothelium should be considered an organ or a specialized tissue. According to the classical definitions of an organ, which require the presence of two or more types of tissues with specific functions, the endothelium is a single layer of epithelial cells and does not strictly meet these criteria. However, various contemporary authors consider it an organ due to its ubiquity, multiple integrative functions, and its systemic role in vascular regulation, inflammation, and thrombosis. It is proposed that, although from an anatomical point of view it is a tissue, its functional importance justifies a conceptual reconsideration to facilitate its comprehensive study in physiology and pathophysiology. [Extracted from the article]
Abstract (Spanish): El artículo se centra en el debate sobre si el endotelio debe considerarse un órgano o un tejido especializado. Según las definiciones clásicas de órgano, que requieren la presencia de dos o más tipos de tejidos con funciones específicas, el endotelio es una monocapa de células epiteliales y no cumple estrictamente con estos criterios. Sin embargo, diversos autores contemporáneos lo consideran un órgano debido a su ubicuidad, múltiples funciones integradoras y su papel sistémico en la regulación vascular, inflamación y trombosis. Se propone que, aunque desde un punto de vista anatómico es un tejido, su importancia funcional justifica una reconsideración conceptual para facilitar su estudio integral en fisiología y fisiopatología. [Extracted from the article]
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Database: MedicLatina
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