Asociación entre fragilidad según el Índice de Fragilidad basado en la Valoración Geriátrica Integral de 10 ítems (FI-CGA-10) y calidad de vida en adultos mayores varones con cáncer.

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Bibliographic Details
Title: Asociación entre fragilidad según el Índice de Fragilidad basado en la Valoración Geriátrica Integral de 10 ítems (FI-CGA-10) y calidad de vida en adultos mayores varones con cáncer.
Alternate Title: Association between frailty measured by the 10-item Comprehensive Geriatric Assessment--based Frailty Index (FICGA-10) and quality of life in older men with cancer.
Authors: Liza Bambaren, Mia C.1 mializab25@gmail.com, Soto Soler, Marife C.1 marifesoto18@gmail.com, Parodi, José F., Runzer Colmenares, Fernando M.1 frunzer@cientifica.edu.pe
Source: Psicooncologia. ene-jun2026, Vol. 23 Issue 1, p23-34. 12p.
Subjects: Cross-sectional method, Poisson distribution, Secondary analysis, Academic medical centers, Frail elderly, Scientific observation, Questionnaires, Cancer patient medical care, Descriptive statistics, Disease prevalence, Decision making in clinical medicine, Quality of life, Geriatric assessment, Men's health, Tumors, Confidence intervals, Phenotypes, Regression analysis, Old age
Geographic Terms: Peru
Abstract (English): Objective: To analyze the association between frailty and quality of life in older men with cancer, comparing frailty measured by the Comprehensive Geriatric Assessment--based 10-item Frailty Index (FI-CGA-10) and the Fried frailty phenotype. Method: An observational analytical cross-sectional study was conducted based on a secondary analysis of a database from the Naval Medical Center in Peru. Data from 891 older men (≥60 years) with a recent diagnosis of cancer undergoing curative treatment were analyzed. Quality of life was assessed using the WHOQoL-Old questionnaire, and frailty was evaluated using the FI-CGA-10 and the Fried phenotype. Prevalence ratios (PR) and 95% confidence intervals were estimated using Poisson regression with robust variance. Results: Frailty was significantly associated with a higher prevalence of poor quality of life. In the adjusted model, frailty according to the Fried phenotype showed an adjusted PR of 1.17 (95% CI: 1.10-1.20), while frailty according to the FI-CGA-10 showed an adjusted PR of 1.10 (95% CI: 1.10-1.20). Polypharmacy was also associated with a higher prevalence of poor quality of life. Conclusions: Frailty is associated with poorer quality of life in older adults with cancer. The systematic assessment of frailty using instruments such as the FI-CGA-10 or the Fried phenotype may contribute to improving comprehensive geriatric assessment and guiding clinical decision-making in oncogeriatric. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Objetivo: Analizar la asociación entre la fragilidad y la calidad de vida en adultos mayores varones con diagnóstico de cáncer, comparando la fragilidad medida mediante el índice de fragilidad basado en la valoración geriátrica integral de 10 ítems (FI-CGA-10) y el fenotipo de Fried. Método: Estudio observacional analítico de corte transversal basado en un análisis secundario de una base de datos del Centro Médico Naval del Perú. Se analizaron datos de 891 adultos mayores varones (≥60 años) con diagnóstico reciente de cáncer en manejo curativo. La calidad de vida se evaluó mediante el cuestionario WHOQoL-Old y la fragilidad mediante el FI-CGA-10 y el fenotipo de Fried. Se estimaron razones de prevalencia (RP) e intervalos de confianza al 95% mediante regresión de Poisson con varianza robusta. Resultados: La fragilidad se asoció significativamente con una mayor prevalencia de calidad de vida no adecuada. En el modelo ajustado, la fragilidad según el fenotipo de Fried mostró una RP ajustada de 1,17 (IC95%: 1,10-1,20), mientras que la fragilidad según el FI-CGA-10 presentó una RP ajustada de 1,10 (IC95%: 1,10-1,20). La polifarmacia también se asoció con una mayor prevalencia de calidad de vida no adecuada. Conclusiones: La fragilidad se relaciona con peor calidad de vida en adultos mayores con cáncer. La evaluación sistemática de la fragilidad mediante instrumentos como el FI-CGA-10 o el fenotipo de Fried puede contribuir a mejorar la valoración geriátrica integral y orientar decisiones clínicas en oncogeriatría. [ABSTRACT FROM AUTHOR]
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Database: MedicLatina
Description
Abstract:Objective: To analyze the association between frailty and quality of life in older men with cancer, comparing frailty measured by the Comprehensive Geriatric Assessment--based 10-item Frailty Index (FI-CGA-10) and the Fried frailty phenotype. Method: An observational analytical cross-sectional study was conducted based on a secondary analysis of a database from the Naval Medical Center in Peru. Data from 891 older men (≥60 years) with a recent diagnosis of cancer undergoing curative treatment were analyzed. Quality of life was assessed using the WHOQoL-Old questionnaire, and frailty was evaluated using the FI-CGA-10 and the Fried phenotype. Prevalence ratios (PR) and 95% confidence intervals were estimated using Poisson regression with robust variance. Results: Frailty was significantly associated with a higher prevalence of poor quality of life. In the adjusted model, frailty according to the Fried phenotype showed an adjusted PR of 1.17 (95% CI: 1.10-1.20), while frailty according to the FI-CGA-10 showed an adjusted PR of 1.10 (95% CI: 1.10-1.20). Polypharmacy was also associated with a higher prevalence of poor quality of life. Conclusions: Frailty is associated with poorer quality of life in older adults with cancer. The systematic assessment of frailty using instruments such as the FI-CGA-10 or the Fried phenotype may contribute to improving comprehensive geriatric assessment and guiding clinical decision-making in oncogeriatric. [ABSTRACT FROM AUTHOR]
ISSN:16967240
DOI:10.5209/psic.108425