Asociación entre fragilidad según el Índice de Fragilidad basado en la Valoración Geriátrica Integral de 10 ítems (FI-CGA-10) y calidad de vida en adultos mayores varones con cáncer.

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Title: Asociación entre fragilidad según el Índice de Fragilidad basado en la Valoración Geriátrica Integral de 10 ítems (FI-CGA-10) y calidad de vida en adultos mayores varones con cáncer.
Alternate Title: Association between frailty measured by the 10-item Comprehensive Geriatric Assessment--based Frailty Index (FICGA-10) and quality of life in older men with cancer.
Authors: Liza Bambaren, Mia C.1 mializab25@gmail.com, Soto Soler, Marife C.1 marifesoto18@gmail.com, Parodi, José F., Runzer Colmenares, Fernando M.1 frunzer@cientifica.edu.pe
Source: Psicooncologia. ene-jun2026, Vol. 23 Issue 1, p23-34. 12p.
Subjects: Cross-sectional method, Poisson distribution, Secondary analysis, Academic medical centers, Frail elderly, Scientific observation, Questionnaires, Cancer patient medical care, Descriptive statistics, Disease prevalence, Decision making in clinical medicine, Quality of life, Geriatric assessment, Men's health, Tumors, Confidence intervals, Phenotypes, Regression analysis, Old age
Geographic Terms: Peru
Abstract (English): Objective: To analyze the association between frailty and quality of life in older men with cancer, comparing frailty measured by the Comprehensive Geriatric Assessment--based 10-item Frailty Index (FI-CGA-10) and the Fried frailty phenotype. Method: An observational analytical cross-sectional study was conducted based on a secondary analysis of a database from the Naval Medical Center in Peru. Data from 891 older men (≥60 years) with a recent diagnosis of cancer undergoing curative treatment were analyzed. Quality of life was assessed using the WHOQoL-Old questionnaire, and frailty was evaluated using the FI-CGA-10 and the Fried phenotype. Prevalence ratios (PR) and 95% confidence intervals were estimated using Poisson regression with robust variance. Results: Frailty was significantly associated with a higher prevalence of poor quality of life. In the adjusted model, frailty according to the Fried phenotype showed an adjusted PR of 1.17 (95% CI: 1.10-1.20), while frailty according to the FI-CGA-10 showed an adjusted PR of 1.10 (95% CI: 1.10-1.20). Polypharmacy was also associated with a higher prevalence of poor quality of life. Conclusions: Frailty is associated with poorer quality of life in older adults with cancer. The systematic assessment of frailty using instruments such as the FI-CGA-10 or the Fried phenotype may contribute to improving comprehensive geriatric assessment and guiding clinical decision-making in oncogeriatric. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Objetivo: Analizar la asociación entre la fragilidad y la calidad de vida en adultos mayores varones con diagnóstico de cáncer, comparando la fragilidad medida mediante el índice de fragilidad basado en la valoración geriátrica integral de 10 ítems (FI-CGA-10) y el fenotipo de Fried. Método: Estudio observacional analítico de corte transversal basado en un análisis secundario de una base de datos del Centro Médico Naval del Perú. Se analizaron datos de 891 adultos mayores varones (≥60 años) con diagnóstico reciente de cáncer en manejo curativo. La calidad de vida se evaluó mediante el cuestionario WHOQoL-Old y la fragilidad mediante el FI-CGA-10 y el fenotipo de Fried. Se estimaron razones de prevalencia (RP) e intervalos de confianza al 95% mediante regresión de Poisson con varianza robusta. Resultados: La fragilidad se asoció significativamente con una mayor prevalencia de calidad de vida no adecuada. En el modelo ajustado, la fragilidad según el fenotipo de Fried mostró una RP ajustada de 1,17 (IC95%: 1,10-1,20), mientras que la fragilidad según el FI-CGA-10 presentó una RP ajustada de 1,10 (IC95%: 1,10-1,20). La polifarmacia también se asoció con una mayor prevalencia de calidad de vida no adecuada. Conclusiones: La fragilidad se relaciona con peor calidad de vida en adultos mayores con cáncer. La evaluación sistemática de la fragilidad mediante instrumentos como el FI-CGA-10 o el fenotipo de Fried puede contribuir a mejorar la valoración geriátrica integral y orientar decisiones clínicas en oncogeriatría. [ABSTRACT FROM AUTHOR]
Copyright of Psicooncologia is the property of Universidad Complutense de Madrid and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
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  Group: Ti
  Data: Asociación entre fragilidad según el Índice de Fragilidad basado en la Valoración Geriátrica Integral de 10 ítems (FI-CGA-10) y calidad de vida en adultos mayores varones con cáncer.
– Name: TitleAlt
  Label: Alternate Title
  Group: TiAlt
  Data: Association between frailty measured by the 10-item Comprehensive Geriatric Assessment--based Frailty Index (FICGA-10) and quality of life in older men with cancer.
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  Label: Authors
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  Data: <searchLink fieldCode="AR" term="%22Liza+Bambaren%2C+Mia+C%2E%22">Liza Bambaren, Mia C.</searchLink><relatesTo>1</relatesTo><i> mializab25@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Soto+Soler%2C+Marife+C%2E%22">Soto Soler, Marife C.</searchLink><relatesTo>1</relatesTo><i> marifesoto18@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Parodi%2C+José+F%2E%22">Parodi, José F.</searchLink><br /><searchLink fieldCode="AR" term="%22Runzer+Colmenares%2C+Fernando+M%2E%22">Runzer Colmenares, Fernando M.</searchLink><relatesTo>1</relatesTo><i> frunzer@cientifica.edu.pe</i>
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  Data: <searchLink fieldCode="JN" term="%22Psicooncologia%22">Psicooncologia</searchLink>. ene-jun2026, Vol. 23 Issue 1, p23-34. 12p.
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  Data: <searchLink fieldCode="DE" term="%22Cross-sectional+method%22">Cross-sectional method</searchLink><br /><searchLink fieldCode="DE" term="%22Poisson+distribution%22">Poisson distribution</searchLink><br /><searchLink fieldCode="DE" term="%22Secondary+analysis%22">Secondary analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Academic+medical+centers%22">Academic medical centers</searchLink><br /><searchLink fieldCode="DE" term="%22Frail+elderly%22">Frail elderly</searchLink><br /><searchLink fieldCode="DE" term="%22Scientific+observation%22">Scientific observation</searchLink><br /><searchLink fieldCode="DE" term="%22Questionnaires%22">Questionnaires</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+patient+medical+care%22">Cancer patient medical care</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+prevalence%22">Disease prevalence</searchLink><br /><searchLink fieldCode="DE" term="%22Decision+making+in+clinical+medicine%22">Decision making in clinical medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink><br /><searchLink fieldCode="DE" term="%22Geriatric+assessment%22">Geriatric assessment</searchLink><br /><searchLink fieldCode="DE" term="%22Men's+health%22">Men's health</searchLink><br /><searchLink fieldCode="DE" term="%22Tumors%22">Tumors</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Phenotypes%22">Phenotypes</searchLink><br /><searchLink fieldCode="DE" term="%22Regression+analysis%22">Regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Old+age%22">Old age</searchLink>
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  Label: Geographic Terms
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  Data: <searchLink fieldCode="DE" term="%22Peru%22">Peru</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Objective: To analyze the association between frailty and quality of life in older men with cancer, comparing frailty measured by the Comprehensive Geriatric Assessment--based 10-item Frailty Index (FI-CGA-10) and the Fried frailty phenotype. Method: An observational analytical cross-sectional study was conducted based on a secondary analysis of a database from the Naval Medical Center in Peru. Data from 891 older men (≥60 years) with a recent diagnosis of cancer undergoing curative treatment were analyzed. Quality of life was assessed using the WHOQoL-Old questionnaire, and frailty was evaluated using the FI-CGA-10 and the Fried phenotype. Prevalence ratios (PR) and 95% confidence intervals were estimated using Poisson regression with robust variance. Results: Frailty was significantly associated with a higher prevalence of poor quality of life. In the adjusted model, frailty according to the Fried phenotype showed an adjusted PR of 1.17 (95% CI: 1.10-1.20), while frailty according to the FI-CGA-10 showed an adjusted PR of 1.10 (95% CI: 1.10-1.20). Polypharmacy was also associated with a higher prevalence of poor quality of life. Conclusions: Frailty is associated with poorer quality of life in older adults with cancer. The systematic assessment of frailty using instruments such as the FI-CGA-10 or the Fried phenotype may contribute to improving comprehensive geriatric assessment and guiding clinical decision-making in oncogeriatric. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Objetivo: Analizar la asociación entre la fragilidad y la calidad de vida en adultos mayores varones con diagnóstico de cáncer, comparando la fragilidad medida mediante el índice de fragilidad basado en la valoración geriátrica integral de 10 ítems (FI-CGA-10) y el fenotipo de Fried. Método: Estudio observacional analítico de corte transversal basado en un análisis secundario de una base de datos del Centro Médico Naval del Perú. Se analizaron datos de 891 adultos mayores varones (≥60 años) con diagnóstico reciente de cáncer en manejo curativo. La calidad de vida se evaluó mediante el cuestionario WHOQoL-Old y la fragilidad mediante el FI-CGA-10 y el fenotipo de Fried. Se estimaron razones de prevalencia (RP) e intervalos de confianza al 95% mediante regresión de Poisson con varianza robusta. Resultados: La fragilidad se asoció significativamente con una mayor prevalencia de calidad de vida no adecuada. En el modelo ajustado, la fragilidad según el fenotipo de Fried mostró una RP ajustada de 1,17 (IC95%: 1,10-1,20), mientras que la fragilidad según el FI-CGA-10 presentó una RP ajustada de 1,10 (IC95%: 1,10-1,20). La polifarmacia también se asoció con una mayor prevalencia de calidad de vida no adecuada. Conclusiones: La fragilidad se relaciona con peor calidad de vida en adultos mayores con cáncer. La evaluación sistemática de la fragilidad mediante instrumentos como el FI-CGA-10 o el fenotipo de Fried puede contribuir a mejorar la valoración geriátrica integral y orientar decisiones clínicas en oncogeriatría. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Psicooncologia is the property of Universidad Complutense de Madrid and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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