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Malformaciones del sistema nervioso central y el raquis en pacientes pediátricos. Experiencia en el Hospital General de México.

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Title: Malformaciones del sistema nervioso central y el raquis en pacientes pediátricos. Experiencia en el Hospital General de México.
Authors: Nava, Patricia Rodríguez1 drapatricia.rodriguez@yahoo.com.mx, Dena Espinoza, Ernesto Javier1, Garduño, Adolfo Hernández2, García, Margarita Fuentes3, Herrera, Carmen Amezcua1, Jarillo, Pedro Armenta1
Source: Anales de Radiologia, Mexico. oct-dic2007, Vol. 6 Issue 4, p263-276. 14p. 18 Black and White Photographs, 3 Diagrams.
Subjects: CENTRAL nervous system abnormalities, PEDIATRICS, MAGNETIC resonance, TOMOGRAPHY, CELL migration, PREGNANCY
Abstract (English): Introduction: The congenital malformations (CM) of the central nervous system (CNS) are caused by an insult to the embryo during the pregnancy. Its etiology is multi factorial. They occur in approximately 0.1-0.9% of births. Objective: To present the frequency and findings through magnetic resonance (MR) and computerized axial tomography (CAT) of the CNS malformations and the rachis in pediatric patients. Material and method: Longitudinal, prospective study, where 81 patients with CNS and quisrachis malformations were studied, 49 of them were male and the other 32 were female. They were evaluated through neuro-clinics, MR studies and in some of the patients with TC. The classification of Boyer R was used. (modified). Results: There were findings of: 1. Organogenesis disorders: a) disorders of closing of the neural tube: 37 cases; b)Diverticulation and segmentation disorders: two patients. c)Furrows formation disorders, and of cellular migration: ten patients. d) Malformations and cysts of the posterior fossa: 46 patients. 2. Histogenesis disorders of the: five cases. e) Other cerebral malformations: 113. f) Congenital malformations of the spine and of the spinal marrow: 29 cases. VII. Vascular malformations: seven cases. Conclusions: MR is the ideal study for cerebral and rachis malformations, been supplemented with TC. The occurrence frequency of CNS and rachis malformations is raised in our environment, because the facility is a concentration Hospital. Existent classifications and the image study for planning the treatment and genetic advice for their association to other malformations and chromosomopathy updating is required. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción: Las malformaciones congénitas (MC) del sistema nervioso central (SNC) están originadas por un insulto al embrión durante el embarazo. Su etiología es multifactorial. Ocurren en aproximadamente 0.1-0.9% de los nacimientos. Objetivo: Presentar la frecuencia y los hallazgos por resonancia magnética (RM) y tomografía computarizada (TC) de las malformaciones del SNC y el raquis en pacientes pediátricos. Material y método: Estudio prospectivo,longitudinal en donde se estudiaron 81 pacientes con malformaciones del SNC y del raquis, 49 del sexo masculino y 32 del sexo femenino. Fueron evaluados a través de la neuroclínica, estudios de RM y en algunos de ellos con TC. Se utilizó la clasificación de Boyer R. (modificado). Resultados: Se encontraron: 1. Trastornos de la organogénesis: a) Trastornos del cierre del tubo neural: 37 casos; b) Trastornos de la diverticulación y segmentación: dos pacientes. c) Trastornos de la formación de surcos y de la migración celular: diez pacientes. d) Malformaciones y quistes de la fosa posterior: 46 pacientes. 2.Trastornos de la histogénesis: cinco casos. e) Otras malformaciones cerebrales: 113. f) Malformaciones congénitas de la columna vertebral y de la médula espinal: 29 casos. VII.Malformaciones vasculares: siete casos. Conclusiones: La RM es el estudio ideal para las malformaciones cerebrales y del raquis, complementándose con la TC. La frecuencia de presentación de las malformaciones del SNC y del Raquis es elevada en nuestro medio, por tratarse de un Hospital de concentración. Se requiere de la actualización en las clasificaciones existentes y el estudio por imagen para planificar el tratamiento y consejo genético por su asociación a otras malformaciones y a cromosomopatías. [ABSTRACT FROM AUTHOR]
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Database: MedicLatina
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Abstract:Introduction: The congenital malformations (CM) of the central nervous system (CNS) are caused by an insult to the embryo during the pregnancy. Its etiology is multi factorial. They occur in approximately 0.1-0.9% of births. Objective: To present the frequency and findings through magnetic resonance (MR) and computerized axial tomography (CAT) of the CNS malformations and the rachis in pediatric patients. Material and method: Longitudinal, prospective study, where 81 patients with CNS and quisrachis malformations were studied, 49 of them were male and the other 32 were female. They were evaluated through neuro-clinics, MR studies and in some of the patients with TC. The classification of Boyer R was used. (modified). Results: There were findings of: 1. Organogenesis disorders: a) disorders of closing of the neural tube: 37 cases; b)Diverticulation and segmentation disorders: two patients. c)Furrows formation disorders, and of cellular migration: ten patients. d) Malformations and cysts of the posterior fossa: 46 patients. 2. Histogenesis disorders of the: five cases. e) Other cerebral malformations: 113. f) Congenital malformations of the spine and of the spinal marrow: 29 cases. VII. Vascular malformations: seven cases. Conclusions: MR is the ideal study for cerebral and rachis malformations, been supplemented with TC. The occurrence frequency of CNS and rachis malformations is raised in our environment, because the facility is a concentration Hospital. Existent classifications and the image study for planning the treatment and genetic advice for their association to other malformations and chromosomopathy updating is required. [ABSTRACT FROM AUTHOR]
ISSN:16652118