GENERALIDADES. EL ASMA COMO PROBLEMA DE SALUD PÚBLICA. DEFINICIÓN. FACTORES DE RIESGO. FENOTIPOS.

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Bibliographic Details
Title:	GENERALIDADES. EL ASMA COMO PROBLEMA DE SALUD PÚBLICA. DEFINICIÓN. FACTORES DE RIESGO. FENOTIPOS.
Alternate Title:	GENERAL. ASTHMA AS A PUBLIC HEALTH PROBLEM. DEFINITION. RISK FACTORS. PHENOTYPES.
Authors:	Villamizar, Isabel Tovar¹, Lamogglia, Maribel Garcia², Meza, Jesus³, Romero, Jesus⁴
Source:	Archivos Venezolanos de Puericultura y Pediatría. abr-jun2010, Vol. 73 Issue 2, p48-54. 7p. 5 Charts, 1 Graph.
Subjects:	EPIDEMIOLOGICAL research, ASTHMA risk factors, WHEEZE, ASTHMA in children, LUNG diseases, WORLD Health Organization, DISEASE prevalence, RESPIRATORY allergy, PUBLIC health, DISEASE risk factors
Abstract (English):	Asthma is one of the most common chronic respiratory disease in childhood. Its prevalence is increasing, it has high morbidity and generates a great number of admissions and enormous costs. The World Health Organization (WHO) estimates that there are over 300 million patients worldwide. In 2005 there were 255,000 deaths attributed to asthma. The International Study of Asthma and Allergies in Childhood (ISAAC), based on questionnaires, is the main source of global research on the prevalence of asthma. According to ISAAC, the prevalence depends on the region of the world that is assessed. In its third phase, Latin American countries participate and the global prevalence and severity of asthma symptoms in children aged 6 to 14 years old is measured. Information is obtained in relation to the presence of wheezing during the last 12 months and the prevalence of symptoms of severity. In Venezuela, 32% of children under fourteen years of age reported having had an episode of asthma or wheezing sometime during their lives. This places Venezuela among the countries with a higher prevalence of asthma in Latin America. Epidemiological data on morbidity and mortality in Venezuela are presented. Risk factors are identified in children who seem to have symptoms of persistent asthma: allergic manifestations, asthmatic parents, wheezing not accompanied by common cold. Epidemiological studies suggest phenotypes with heterogeneous conditions which follow a final common pathway characterized by recurrent bronchial obstruction. Three of these are "transient early wheezing", the "non-atopic wheezing preschooler" and "asthma /atopic wheezing." [ABSTRACT FROM AUTHOR]
Abstract (Spanish):	El asma es una de las enfermedades respiratorias mas comunes, de evolucion cronica en la infancia y su prevalencia esta aumentando; su morbilidad es muy alta, genera gran cantidad de hospitalizaciones, costos enormes, no se cuenta con tratamiento curativo. La Organizacion Mundial de la Salud (OMS) calcula en la actualidad 300 millones de pacientes en el mundo. En el 2005 fallecieron 255.000 personas. El Estudio Internacional sobre Asma, Alergias en la Infancia (ISAAC) basado en interrogatorio, es la principal fuente de investigacion mundial sobre prevalencia del asma, y plantea que la prevalencia depende de cada lugar del mundo que se evalue. En su fase tres participan paises latinoamericanos y mide la prevalencia global en menores de catorce anos. La informacion se obtiene en relacion a la presencia de sibilancias en los ultimos doce meses y la prevalencia de sintomas de severidad. En Venezuela, 32% de los menores de 14 anos reporta haber presentado alguna vez en su vida episodio de asma o sibilancias. Esto nos ubica entre los paises con mayor prevalencia de esta enfermedad en Latinoamerica. Se senalan datos epidemiologicos de morbilidad y mortalidad en Venezuela. Factores de riesgo son identificados en aquellos ninos que parecieran tener asma persistente: manifestaciones alergicas, asma en los padres, sibilancias no acompanadas de catarro comun. Estudios epidemiologicos sugieren fenotipos con condiciones heterogeneas que siguen una via comun caracterizada por obstruccion bronquial recurrente. Tres de esos “sibilantes transitorios precoces”, los “preescolares sibilantes no atopicos” y los “asmaticos/sibilantes atopicos”. [ABSTRACT FROM AUTHOR]
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Database:	MedicLatina

Description
Abstract:	Asthma is one of the most common chronic respiratory disease in childhood. Its prevalence is increasing, it has high morbidity and generates a great number of admissions and enormous costs. The World Health Organization (WHO) estimates that there are over 300 million patients worldwide. In 2005 there were 255,000 deaths attributed to asthma. The International Study of Asthma and Allergies in Childhood (ISAAC), based on questionnaires, is the main source of global research on the prevalence of asthma. According to ISAAC, the prevalence depends on the region of the world that is assessed. In its third phase, Latin American countries participate and the global prevalence and severity of asthma symptoms in children aged 6 to 14 years old is measured. Information is obtained in relation to the presence of wheezing during the last 12 months and the prevalence of symptoms of severity. In Venezuela, 32% of children under fourteen years of age reported having had an episode of asthma or wheezing sometime during their lives. This places Venezuela among the countries with a higher prevalence of asthma in Latin America. Epidemiological data on morbidity and mortality in Venezuela are presented. Risk factors are identified in children who seem to have symptoms of persistent asthma: allergic manifestations, asthmatic parents, wheezing not accompanied by common cold. Epidemiological studies suggest phenotypes with heterogeneous conditions which follow a final common pathway characterized by recurrent bronchial obstruction. Three of these are "transient early wheezing", the "non-atopic wheezing preschooler" and "asthma /atopic wheezing." [ABSTRACT FROM AUTHOR]
ISSN:	00040649