SEROTONINA: UN MENSAJERO ENTRE EL CEREBRO, EL INTESTINO Y EL HUESO.
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| Title: | SEROTONINA: UN MENSAJERO ENTRE EL CEREBRO, EL INTESTINO Y EL HUESO. |
|---|---|
| Alternate Title: | SEROTONIN: A MESSENGER BETWEEN THE BRAIN, THE GUT, AND BONE. |
| Authors: | Sánchez, Ariel1 asanchez@cimero.org.ar |
| Source: | Actualizaciones en Osteología. 2012, Vol. 8 Issue 2, p79-85. 7p. 1 Diagram. |
| Subjects: | SEROTONIN antagonists, SEROTONIN, OSTEOPENIA, AFFECTIVE disorders, MENTAL health services, RISK factors of fractures, OSTEOPOROSIS treatment |
| Abstract (English): | In the last few years there has been an accumulation of knowledge about the role of serotonin on bone turnovei There seems to be a dual effect, with brain serotonin having an anabolic influence on bone, and gut serotonin inhibiting osteoblastic function, although there is a recent controversy about this. Selective serotonin reuptake inhibitors, widely used to treat mood disorders, induce osteopenia and increase fracture risk Approaches are being studied to modulate the production of gut serotonin as a possible treatment against osteoporosis. However, there is a long road ahead before translating basic findings to clinical practice. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | En los ültimos años ha crecido el conocimiento sobre el papel de la serotonina en el recambio óseo. Parece haber un efecto dual, con la serotonina cerebral ejerciendo un efecto anabólico sobre el hueso y la serotonina intestinal frenando la función osteoblástica, pero han surgido controversias recientes al respecto. Los inhibidores selectivos de la recaptación de serotonina, ampliamente usados para tratar desárdenes afectivos, inducen osteopenia y aumentan el riesgo de fracturas. Se abre a posibilidad de intervenir farmacolópara modular la producción de serotonina intestinal como eventual tratamiento de la osteoporosis, pero falta todavía recorrer un largo camino para trasladar los hallazgos básicos a la clinica. [ABSTRACT FROM AUTHOR] |
| Copyright of Actualizaciones en Osteología is the property of Asociacion Argentina de Osteologia y Metabolismo Mineral and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 79756709 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: SEROTONINA: UN MENSAJERO ENTRE EL CEREBRO, EL INTESTINO Y EL HUESO. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: SEROTONIN: A MESSENGER BETWEEN THE BRAIN, THE GUT, AND BONE. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sánchez%2C+Ariel%22">Sánchez, Ariel</searchLink><relatesTo>1</relatesTo><i> asanchez@cimero.org.ar</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Actualizaciones+en+Osteología%22">Actualizaciones en Osteología</searchLink>. 2012, Vol. 8 Issue 2, p79-85. 7p. 1 Diagram. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22SEROTONIN+antagonists%22">SEROTONIN antagonists</searchLink><br /><searchLink fieldCode="DE" term="%22SEROTONIN%22">SEROTONIN</searchLink><br /><searchLink fieldCode="DE" term="%22OSTEOPENIA%22">OSTEOPENIA</searchLink><br /><searchLink fieldCode="DE" term="%22AFFECTIVE+disorders%22">AFFECTIVE disorders</searchLink><br /><searchLink fieldCode="DE" term="%22MENTAL+health+services%22">MENTAL health services</searchLink><br /><searchLink fieldCode="DE" term="%22RISK+factors+of+fractures%22">RISK factors of fractures</searchLink><br /><searchLink fieldCode="DE" term="%22OSTEOPOROSIS+treatment%22">OSTEOPOROSIS treatment</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: In the last few years there has been an accumulation of knowledge about the role of serotonin on bone turnovei There seems to be a dual effect, with brain serotonin having an anabolic influence on bone, and gut serotonin inhibiting osteoblastic function, although there is a recent controversy about this. Selective serotonin reuptake inhibitors, widely used to treat mood disorders, induce osteopenia and increase fracture risk Approaches are being studied to modulate the production of gut serotonin as a possible treatment against osteoporosis. However, there is a long road ahead before translating basic findings to clinical practice. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: En los ültimos años ha crecido el conocimiento sobre el papel de la serotonina en el recambio óseo. Parece haber un efecto dual, con la serotonina cerebral ejerciendo un efecto anabólico sobre el hueso y la serotonina intestinal frenando la función osteoblástica, pero han surgido controversias recientes al respecto. Los inhibidores selectivos de la recaptación de serotonina, ampliamente usados para tratar desárdenes afectivos, inducen osteopenia y aumentan el riesgo de fracturas. Se abre a posibilidad de intervenir farmacolópara modular la producción de serotonina intestinal como eventual tratamiento de la osteoporosis, pero falta todavía recorrer un largo camino para trasladar los hallazgos básicos a la clinica. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Actualizaciones en Osteología is the property of Asociacion Argentina de Osteologia y Metabolismo Mineral and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=79756709 |
| RecordInfo | BibRecord: BibEntity: Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 7 StartPage: 79 Subjects: – SubjectFull: SEROTONIN antagonists Type: general – SubjectFull: SEROTONIN Type: general – SubjectFull: OSTEOPENIA Type: general – SubjectFull: AFFECTIVE disorders Type: general – SubjectFull: MENTAL health services Type: general – SubjectFull: RISK factors of fractures Type: general – SubjectFull: OSTEOPOROSIS treatment Type: general Titles: – TitleFull: SEROTONINA: UN MENSAJERO ENTRE EL CEREBRO, EL INTESTINO Y EL HUESO. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sánchez, Ariel IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2012 Type: published Y: 2012 Identifiers: – Type: issn-print Value: 16698975 Numbering: – Type: volume Value: 8 – Type: issue Value: 2 Titles: – TitleFull: Actualizaciones en Osteología Type: main |
| ResultId | 1 |
