Correlación de la gravedad de urticaria crónica y calidad de vida.

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Bibliographic Details
Title:	Correlación de la gravedad de urticaria crónica y calidad de vida.
Authors:	Aguilar-Hinojosa, Nadia K.¹ nNadiaaguilarhino@hotmail.com, Segura-Méndez, Nora Hilda², Lugo-Reyes, Saúl Oswaldo²
Source:	Revista Alergia de Mexico. oct-dic2012, Vol. 59 Issue 4, p180-186. 7p.
Subjects:	URTICARIA, QUALITY of life, ANTI-immunoglobulin E autoantibodies, SKIN tests, QUESTIONNAIRES
Abstract (English):	Background: Chronic urticaria (CU) is characterized by the presence of wheals and pruritus in the majority of days for more than six weeks, affecting quality of life as in patients with ischemic cardiopathy. There is a validated specific instrument in Spanish to assess quality of life in chronic urticaria (CU-Q2oL). Objective: To show the association between severity of CU and quality of life in patients according to urticaria activity score (UAS) and questionnaire of quality of life in chronic urticaria (CU-Q2oL), respectively. Methods: Instruments of Urticaria Activity Scoring (UAS) and a questionnaire of quality of life were applied to a group of patients with UC. Some causes of urticaria were assessed by means of history and physical, laboratory tests and autologous serum skin test. Results: Fifty patients with UC were included, of whom 82% were women, with a mean age of 41 years. We observed moderate severity in 58%. Sixty percent of the patients presented a positive anti-IgE autoantibodies test; idiopathic chronic urticaria was seen in 24% of the patients and allergic etiology in 20%. The main impairment in quality of life was related to the pruritus and the function. The relationship between severity and quality of life was meaningful: r²= 0.511 y p<0.0001, with an inverse proportional relation. Conclusions: We found a clear inverse correlation between the instruments of severity of urticaria and quality of life. The application of both instruments can be very useful in the care of patients with chronic urticaria. [ABSTRACT FROM AUTHOR]
Abstract (Spanish):	Antecedentes: la urticaria crónica se caracteriza por la coexistencia de ronchas y prurito la mayor parte de los días durante más de seis semanas, con afectación en la calidad de vida similar a pacientes con cardiopatía isquémica. Existe un instrumento específico validado en español para evaluar la calidad de vida en urticaria crónica (CU-Q2oL). Objetivo: mostrar la asociación entre la severidad de la urticaria crónica y la calidad de vida de los pacientes de acuerdo con la puntuación de la actividad de urticaria (UAS) y cuestionario de calidad de vida en urticaria crónica (CU-Q2oL), respectivamente. Métodos: estudio transversal consistente en la aplicación de los instrumentos de actividad de la urticaria (UAS) y cuestionario de calidad de vida en urticaria crónica (CU-Q2oL) a un grupo de pacientes con urticaria crónica. Mediante la historia clínica, estudios de laboratorio y la prueba cutánea de suero autólogo se evaluaron algunas causas de la urticaria. Resultados: participaron 50 pacientes con urticaria crónica, 82% mujeres, con edad promedio de 41 años. Se observó severidad moderada en 58%. El 60% de los pacientes tuvo prueba positiva de autoanticuerpos anti-IgE; la urticaria crónica idiopática se encontró en 24% de los pacientes y la de causa alérgica en 20%. El principal deterioro en la calidad de vida se relacionó con prurito y la función. La relación entre severidad y calidad de vida fue significativa: r²= 0.511 y p<0.0001, con una relación inversamente proporcional. Conclusiones: se encontró una clara correlación inversa entre los instrumentos de severidad de la urticaria y la calidad de vida. La aplicación de ambos instrumentos puede ser muy útil en la atención de pacientes con urticaria crónica. [ABSTRACT FROM AUTHOR]
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Database:	MedicLatina

Description
Abstract:	Background: Chronic urticaria (CU) is characterized by the presence of wheals and pruritus in the majority of days for more than six weeks, affecting quality of life as in patients with ischemic cardiopathy. There is a validated specific instrument in Spanish to assess quality of life in chronic urticaria (CU-Q2oL). Objective: To show the association between severity of CU and quality of life in patients according to urticaria activity score (UAS) and questionnaire of quality of life in chronic urticaria (CU-Q2oL), respectively. Methods: Instruments of Urticaria Activity Scoring (UAS) and a questionnaire of quality of life were applied to a group of patients with UC. Some causes of urticaria were assessed by means of history and physical, laboratory tests and autologous serum skin test. Results: Fifty patients with UC were included, of whom 82% were women, with a mean age of 41 years. We observed moderate severity in 58%. Sixty percent of the patients presented a positive anti-IgE autoantibodies test; idiopathic chronic urticaria was seen in 24% of the patients and allergic etiology in 20%. The main impairment in quality of life was related to the pruritus and the function. The relationship between severity and quality of life was meaningful: r²= 0.511 y p<0.0001, with an inverse proportional relation. Conclusions: We found a clear inverse correlation between the instruments of severity of urticaria and quality of life. The application of both instruments can be very useful in the care of patients with chronic urticaria. [ABSTRACT FROM AUTHOR]
ISSN:	00025151