Bibliographic Details
| Title: |
Evaluación sistemática de la biopsia de médula ósea en casos de sospecha de mielofibrosis primaria. Propuesta de informe diagnóstico estandarizado. Consenso de expertos de las SEAP/SEHH. |
| Alternate Title: |
Systematic evaluation and standardised reporting of cases with suspicion of primary myelofibrosis. Consensus of SEAP/SEHH hematopathology experts. |
| Authors: |
Montes-Moreno, Santiago1 smontes@humv.es, Acevedo, Agustín2, Besses, Carlos3, Ferrández, Antonio4, Fraga, Máximo5, García, Juan F.6, García, Mar7, Mayordomo-Aranda, Empar8, Menárguez, Javier9, Calzada, Reyes10, Raya, José María11, Rozman, María12 |
| Source: |
Revista Española de Patología. oct-dic2014, Vol. 47 Issue 4, p210-217. 8p. 2 Diagrams, 4 Charts. |
| Subjects: |
BONE marrow examination, DELPHI method, BIOPSY, MYELOFIBROSIS, PATHOLOGICAL laboratories, LABORATORY reports, HISTOPATHOLOGY, DIFFERENTIAL diagnosis, STANDARDS, DIAGNOSIS |
| Abstract (English): |
A consensus based on Delphi methodology was developed to produce a guide for the evaluation and reporting of bone marrow biopsies in patients with a clinical suspicion of myeloproliferative neoplasm with fibrosis. Ten expert haematopathologists formulated a questionnaire including: clinical and laboratory data required before regarding a biopsy suspicious for primary myelofibrosis (PMF), descriptive aspects to be reported and the main histopathological differential diagnoses to be considered. It was circulated among 37 hematopathologists and consensus was defined when more than 70% of the experts ''strongly agreed'' or ''agreed'' after two rounds. The recommendations gave rise to a proposal for a standardized diagnostic report form to aid in the diagnostic workup and homogeneous reporting of cases with a clinical suspicion of PMF. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
Se ha elaborado un consenso aplicando la metodología Delphi para acordar cuál debe ser la sistemática de evaluación e información de las biopsias de médula ósea en las neoplasias mieloproliferativas crónicas, especialmente en casos de mielofibrosis primaria (MFP). Un panel de 10 expertos hematopatólogos ha elaborado un cuestionario que se ha remitido a 37 hematopatólogos con preguntas acerca de los datos clínicos, analíticos y moleculares a conocer en la fase pre-analítica, parámetros histopatológicos a evaluar y contenido del informe diagnóstico final. Se realizaron 2 rondas buscando un consenso mínimo del 70% para los parámetros imprescindibles y recomendables. A partir de los resultados del consenso se elabora y propone un prototipo de informe histopatológico para informar de manera homogénea y reproducible los casos de MFP. [ABSTRACT FROM AUTHOR] |
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| Database: |
MedicLatina |
