In hybridoma cultures, deprivation of any single amino acid leads to apoptotic death, which is suppressed by the expression of the bcl-2 gene.

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Bibliographic Details
Title: In hybridoma cultures, deprivation of any single amino acid leads to apoptotic death, which is suppressed by the expression of the bcl-2 gene.
Authors: Simpson NH; Centre for Bioprocess Engineering, School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom., Singh RP, Perani A, Goldenzon C, Al-Rubeai M
Source: Biotechnology and bioengineering [Biotechnol Bioeng] 1998 Jul 05; Vol. 59 (1), pp. 90-8.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print Cited Medium: Print ISSN: 0006-3592 (Print) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:0006-3592
DOI:10.1002/(sici)1097-0290(19980705)59:1<90::aid-bit12>3.0.co;2-6