Design and synthesis of potent non-polyglutamatable quinazoline antifolate thymidylate synthase inhibitors.

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Title: Design and synthesis of potent non-polyglutamatable quinazoline antifolate thymidylate synthase inhibitors.
Authors: Marsham PR; AstraZeneca, Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, England., Wardleworth JM, Boyle FT, Hennequin LF, Kimbell R, Brown M, Jackman AL
Source: Journal of medicinal chemistry [J Med Chem] 1999 Sep 23; Vol. 42 (19), pp. 3809-20.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print <i>Cited Medium: </i>Print <i>ISSN: </i>0022-2623 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1021/jm9803727
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      – Code: eng
        Text: English
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        StartPage: 3809
    Titles:
      – TitleFull: Design and synthesis of potent non-polyglutamatable quinazoline antifolate thymidylate synthase inhibitors.
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            NameFull: Marsham PR
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            NameFull: Wardleworth JM
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            NameFull: Boyle FT
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            NameFull: Hennequin LF
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            NameFull: Kimbell R
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            NameFull: Brown M
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            NameFull: Jackman AL
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            – D: 23
              M: 09
              Text: 1999 Sep 23
              Type: published
              Y: 1999
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              Value: 42
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              Value: 19
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            – TitleFull: Journal of medicinal chemistry
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