Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.

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Bibliographic Details
Title: Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.
Authors: Kasibhatla SR; Department of Chemistry, Biogen Idec, Inc., 5200 Research Place, San Diego, CA 92122, USA. srinivasrao.kasibhatla@biogenidec.com, Hong K, Biamonte MA, Busch DJ, Karjian PL, Sensintaffar JL, Kamal A, Lough RE, Brekken J, Lundgren K, Grecko R, Timony GA, Ran Y, Mansfield R, Fritz LC, Ulm E, Burrows FJ, Boehm MF
Source: Journal of medicinal chemistry [J Med Chem] 2007 Jun 14; Vol. 50 (12), pp. 2767-78. Date of Electronic Publication: 2007 May 08.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:0022-2623
DOI:10.1021/jm050752+