Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.

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Title: Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.
Authors: Kasibhatla SR; Department of Chemistry, Biogen Idec, Inc., 5200 Research Place, San Diego, CA 92122, USA. srinivasrao.kasibhatla@biogenidec.com, Hong K, Biamonte MA, Busch DJ, Karjian PL, Sensintaffar JL, Kamal A, Lough RE, Brekken J, Lundgren K, Grecko R, Timony GA, Ran Y, Mansfield R, Fritz LC, Ulm E, Burrows FJ, Boehm MF
Source: Journal of medicinal chemistry [J Med Chem] 2007 Jun 14; Vol. 50 (12), pp. 2767-78. Date of Electronic Publication: 2007 May 08.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.
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  Data: <searchLink fieldCode="AU" term="%22Kasibhatla+SR%22">Kasibhatla SR</searchLink>; Department of Chemistry, Biogen Idec, Inc., 5200 Research Place, San Diego, CA 92122, USA. srinivasrao.kasibhatla@biogenidec.com<br /><searchLink fieldCode="AU" term="%22Hong+K%22">Hong K</searchLink><br /><searchLink fieldCode="AU" term="%22Biamonte+MA%22">Biamonte MA</searchLink><br /><searchLink fieldCode="AU" term="%22Busch+DJ%22">Busch DJ</searchLink><br /><searchLink fieldCode="AU" term="%22Karjian+PL%22">Karjian PL</searchLink><br /><searchLink fieldCode="AU" term="%22Sensintaffar+JL%22">Sensintaffar JL</searchLink><br /><searchLink fieldCode="AU" term="%22Kamal+A%22">Kamal A</searchLink><br /><searchLink fieldCode="AU" term="%22Lough+RE%22">Lough RE</searchLink><br /><searchLink fieldCode="AU" term="%22Brekken+J%22">Brekken J</searchLink><br /><searchLink fieldCode="AU" term="%22Lundgren+K%22">Lundgren K</searchLink><br /><searchLink fieldCode="AU" term="%22Grecko+R%22">Grecko R</searchLink><br /><searchLink fieldCode="AU" term="%22Timony+GA%22">Timony GA</searchLink><br /><searchLink fieldCode="AU" term="%22Ran+Y%22">Ran Y</searchLink><br /><searchLink fieldCode="AU" term="%22Mansfield+R%22">Mansfield R</searchLink><br /><searchLink fieldCode="AU" term="%22Fritz+LC%22">Fritz LC</searchLink><br /><searchLink fieldCode="AU" term="%22Ulm+E%22">Ulm E</searchLink><br /><searchLink fieldCode="AU" term="%22Burrows+FJ%22">Burrows FJ</searchLink><br /><searchLink fieldCode="AU" term="%22Boehm+MF%22">Boehm MF</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2007 Jun 14; Vol. 50 (12), pp. 2767-78. <i>Date of Electronic Publication: </i>2007 May 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>0022-2623 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1021/jm050752+
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        Text: English
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              Text: 2007 Jun 14
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