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Identification of 4-aminopyrazolylpyrimidines as potent inhibitors of Trk kinases.

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Title: Identification of 4-aminopyrazolylpyrimidines as potent inhibitors of Trk kinases.
Authors: Wang T; Department of Cancer Chemistry, AstraZeneca R&D Boston, Waltham, Massachusetts 02451, USA. tao.wang@astrazeneca.com, Lamb ML, Scott DA, Wang H, Block MH, Lyne PD, Lee JW, Davies AM, Zhang HJ, Zhu Y, Gu F, Han Y, Wang B, Mohr PJ, Kaus RJ, Josey JA, Hoffmann E, Thress K, Macintyre T, Wang H, Omer CA, Yu D
Source: Journal of medicinal chemistry [J Med Chem] 2008 Aug 14; Vol. 51 (15), pp. 4672-84. Date of Electronic Publication: 2008 Jul 23.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Identification of 4-aminopyrazolylpyrimidines as potent inhibitors of Trk kinases.
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  Data: <searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Department of Cancer Chemistry, AstraZeneca R&D Boston, Waltham, Massachusetts 02451, USA. tao.wang@astrazeneca.com<br /><searchLink fieldCode="AU" term="%22Lamb+ML%22">Lamb ML</searchLink><br /><searchLink fieldCode="AU" term="%22Scott+DA%22">Scott DA</searchLink><br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink><br /><searchLink fieldCode="AU" term="%22Block+MH%22">Block MH</searchLink><br /><searchLink fieldCode="AU" term="%22Lyne+PD%22">Lyne PD</searchLink><br /><searchLink fieldCode="AU" term="%22Lee+JW%22">Lee JW</searchLink><br /><searchLink fieldCode="AU" term="%22Davies+AM%22">Davies AM</searchLink><br /><searchLink fieldCode="AU" term="%22Zhang+HJ%22">Zhang HJ</searchLink><br /><searchLink fieldCode="AU" term="%22Zhu+Y%22">Zhu Y</searchLink><br /><searchLink fieldCode="AU" term="%22Gu+F%22">Gu F</searchLink><br /><searchLink fieldCode="AU" term="%22Han+Y%22">Han Y</searchLink><br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink><br /><searchLink fieldCode="AU" term="%22Mohr+PJ%22">Mohr PJ</searchLink><br /><searchLink fieldCode="AU" term="%22Kaus+RJ%22">Kaus RJ</searchLink><br /><searchLink fieldCode="AU" term="%22Josey+JA%22">Josey JA</searchLink><br /><searchLink fieldCode="AU" term="%22Hoffmann+E%22">Hoffmann E</searchLink><br /><searchLink fieldCode="AU" term="%22Thress+K%22">Thress K</searchLink><br /><searchLink fieldCode="AU" term="%22Macintyre+T%22">Macintyre T</searchLink><br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink><br /><searchLink fieldCode="AU" term="%22Omer+CA%22">Omer CA</searchLink><br /><searchLink fieldCode="AU" term="%22Yu+D%22">Yu D</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2008 Aug 14; Vol. 51 (15), pp. 4672-84. <i>Date of Electronic Publication: </i>2008 Jul 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=18646745
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              Text: 2008 Aug 14
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