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Structure-based design of substituted biphenyl ethylene ethers as ligands binding in the hydrophobic pocket of gp41 and blocking the helical bundle formation.

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Title: Structure-based design of substituted biphenyl ethylene ethers as ligands binding in the hydrophobic pocket of gp41 and blocking the helical bundle formation.
Authors: Liu B; Locus Pharmaceuticals, Inc., Four Valley Square, 512 Township Line Road, Blue Bell, PA 19422, USA. bliu@locuspharma.com, Joseph RW, Dorsey BD, Schiksnis RA, Northrop K, Bukhtiyarova M, Springman EB
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Oct 01; Vol. 19 (19), pp. 5693-7. Date of Electronic Publication: 2009 Aug 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 19699090
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Structure-based design of substituted biphenyl ethylene ethers as ligands binding in the hydrophobic pocket of gp41 and blocking the helical bundle formation.
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  Data: <searchLink fieldCode="AU" term="%22Liu+B%22">Liu B</searchLink>; Locus Pharmaceuticals, Inc., Four Valley Square, 512 Township Line Road, Blue Bell, PA 19422, USA. bliu@locuspharma.com<br /><searchLink fieldCode="AU" term="%22Joseph+RW%22">Joseph RW</searchLink><br /><searchLink fieldCode="AU" term="%22Dorsey+BD%22">Dorsey BD</searchLink><br /><searchLink fieldCode="AU" term="%22Schiksnis+RA%22">Schiksnis RA</searchLink><br /><searchLink fieldCode="AU" term="%22Northrop+K%22">Northrop K</searchLink><br /><searchLink fieldCode="AU" term="%22Bukhtiyarova+M%22">Bukhtiyarova M</searchLink><br /><searchLink fieldCode="AU" term="%22Springman+EB%22">Springman EB</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2009 Oct 01; Vol. 19 (19), pp. 5693-7. <i>Date of Electronic Publication: </i>2009 Aug 08.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9107377 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1464-3405 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220960894X%22">0960894X </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem Lett <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.bmcl.2009.08.018
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      – Code: eng
        Text: English
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        StartPage: 5693
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      – TitleFull: Structure-based design of substituted biphenyl ethylene ethers as ligands binding in the hydrophobic pocket of gp41 and blocking the helical bundle formation.
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            NameFull: Liu B
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            NameFull: Joseph RW
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            NameFull: Dorsey BD
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            NameFull: Schiksnis RA
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            NameFull: Northrop K
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            NameFull: Bukhtiyarova M
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            NameFull: Springman EB
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            – D: 01
              M: 10
              Text: 2009 Oct 01
              Type: published
              Y: 2009
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              Value: 1464-3405
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              Value: 19
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              Value: 19
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            – TitleFull: Bioorganic & medicinal chemistry letters
              Type: main
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