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Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety.

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Title: Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety.
Authors: Shaw SJ; Department of Chemistry, Kosan Biosciences, Inc., Hayward, California 94545, USA. sshaw@rigel.com, Chen Y, Zheng H, Fu H, Burlingame MA, Marquez S, Li Y, Claypool M, Carreras CW, Crumb W, Hardy DJ, Myles DC, Liu Y
Source: Journal of medicinal chemistry [J Med Chem] 2009 Nov 12; Vol. 52 (21), pp. 6851-9.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety.
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  Data: <searchLink fieldCode="AU" term="%22Shaw+SJ%22">Shaw SJ</searchLink>; Department of Chemistry, Kosan Biosciences, Inc., Hayward, California 94545, USA. sshaw@rigel.com<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink><br /><searchLink fieldCode="AU" term="%22Zheng+H%22">Zheng H</searchLink><br /><searchLink fieldCode="AU" term="%22Fu+H%22">Fu H</searchLink><br /><searchLink fieldCode="AU" term="%22Burlingame+MA%22">Burlingame MA</searchLink><br /><searchLink fieldCode="AU" term="%22Marquez+S%22">Marquez S</searchLink><br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink><br /><searchLink fieldCode="AU" term="%22Claypool+M%22">Claypool M</searchLink><br /><searchLink fieldCode="AU" term="%22Carreras+CW%22">Carreras CW</searchLink><br /><searchLink fieldCode="AU" term="%22Crumb+W%22">Crumb W</searchLink><br /><searchLink fieldCode="AU" term="%22Hardy+DJ%22">Hardy DJ</searchLink><br /><searchLink fieldCode="AU" term="%22Myles+DC%22">Myles DC</searchLink><br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2009 Nov 12; Vol. 52 (21), pp. 6851-9.
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        Value: 10.1021/jm901107f
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              Text: 2009 Nov 12
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