Phase I pharmacokinetic and pharmacodynamic study of triciribine phosphate monohydrate, a small-molecule inhibitor of AKT phosphorylation, in adult subjects with solid tumors containing activated AKT.

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Title: Phase I pharmacokinetic and pharmacodynamic study of triciribine phosphate monohydrate, a small-molecule inhibitor of AKT phosphorylation, in adult subjects with solid tumors containing activated AKT.
Authors: Garrett CR; Department of Experimental Therapeutics, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612-9497, USA. cgarrett@mdanderson.org, Coppola D, Wenham RM, Cubitt CL, Neuger AM, Frost TJ, Lush RM, Sullivan DM, Cheng JQ, Sebti SM
Source: Investigational new drugs [Invest New Drugs] 2011 Dec; Vol. 29 (6), pp. 1381-9. Date of Electronic Publication: 2010 Jul 20.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-0646 (Electronic) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-0646
DOI:10.1007/s10637-010-9479-2