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Phase I pharmacokinetic and pharmacodynamic study of triciribine phosphate monohydrate, a small-molecule inhibitor of AKT phosphorylation, in adult subjects with solid tumors containing activated AKT.

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Title: Phase I pharmacokinetic and pharmacodynamic study of triciribine phosphate monohydrate, a small-molecule inhibitor of AKT phosphorylation, in adult subjects with solid tumors containing activated AKT.
Authors: Garrett CR; Department of Experimental Therapeutics, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612-9497, USA. cgarrett@mdanderson.org, Coppola D, Wenham RM, Cubitt CL, Neuger AM, Frost TJ, Lush RM, Sullivan DM, Cheng JQ, Sebti SM
Source: Investigational new drugs [Invest New Drugs] 2011 Dec; Vol. 29 (6), pp. 1381-9. Date of Electronic Publication: 2010 Jul 20.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-0646 (Electronic) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Garrett+CR%22">Garrett CR</searchLink>; Department of Experimental Therapeutics, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612-9497, USA. cgarrett@mdanderson.org<br /><searchLink fieldCode="AU" term="%22Coppola+D%22">Coppola D</searchLink><br /><searchLink fieldCode="AU" term="%22Wenham+RM%22">Wenham RM</searchLink><br /><searchLink fieldCode="AU" term="%22Cubitt+CL%22">Cubitt CL</searchLink><br /><searchLink fieldCode="AU" term="%22Neuger+AM%22">Neuger AM</searchLink><br /><searchLink fieldCode="AU" term="%22Frost+TJ%22">Frost TJ</searchLink><br /><searchLink fieldCode="AU" term="%22Lush+RM%22">Lush RM</searchLink><br /><searchLink fieldCode="AU" term="%22Sullivan+DM%22">Sullivan DM</searchLink><br /><searchLink fieldCode="AU" term="%22Cheng+JQ%22">Cheng JQ</searchLink><br /><searchLink fieldCode="AU" term="%22Sebti+SM%22">Sebti SM</searchLink>
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  Data: <searchLink fieldCode="JN" term="%228309330%22">Investigational new drugs</searchLink> [Invest New Drugs] 2011 Dec; Vol. 29 (6), pp. 1381-9. <i>Date of Electronic Publication: </i>2010 Jul 20.
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  Data: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8309330 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-0646 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201676997%22">01676997 </searchLink><i>NLM ISO Abbreviation: </i>Invest New Drugs <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10637-010-9479-2
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              Text: 2011 Dec
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