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In vitro and in vivo evaluation of 6-aminopyrazolyl-pyridine-3-carbonitriles as JAK2 kinase inhibitors.

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Title: In vitro and in vivo evaluation of 6-aminopyrazolyl-pyridine-3-carbonitriles as JAK2 kinase inhibitors.
Authors: Wang T; Department of Cancer Chemistry, Oncology Innovative Medicines Unit, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, MA 02451, USA. tao.wang@astrazeneca.com, Ioannidis S, Almeida L, Block MH, Davies AM, Lamb ML, Scott DA, Su M, Zhang HJ, Alimzhanov M, Bebernitz G, Bell K, Zinda M
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2011 May 15; Vol. 21 (10), pp. 2958-61. Date of Electronic Publication: 2011 Mar 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: In vitro and in vivo evaluation of 6-aminopyrazolyl-pyridine-3-carbonitriles as JAK2 kinase inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Department of Cancer Chemistry, Oncology Innovative Medicines Unit, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, MA 02451, USA. tao.wang@astrazeneca.com<br /><searchLink fieldCode="AU" term="%22Ioannidis+S%22">Ioannidis S</searchLink><br /><searchLink fieldCode="AU" term="%22Almeida+L%22">Almeida L</searchLink><br /><searchLink fieldCode="AU" term="%22Block+MH%22">Block MH</searchLink><br /><searchLink fieldCode="AU" term="%22Davies+AM%22">Davies AM</searchLink><br /><searchLink fieldCode="AU" term="%22Lamb+ML%22">Lamb ML</searchLink><br /><searchLink fieldCode="AU" term="%22Scott+DA%22">Scott DA</searchLink><br /><searchLink fieldCode="AU" term="%22Su+M%22">Su M</searchLink><br /><searchLink fieldCode="AU" term="%22Zhang+HJ%22">Zhang HJ</searchLink><br /><searchLink fieldCode="AU" term="%22Alimzhanov+M%22">Alimzhanov M</searchLink><br /><searchLink fieldCode="AU" term="%22Bebernitz+G%22">Bebernitz G</searchLink><br /><searchLink fieldCode="AU" term="%22Bell+K%22">Bell K</searchLink><br /><searchLink fieldCode="AU" term="%22Zinda+M%22">Zinda M</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2011 May 15; Vol. 21 (10), pp. 2958-61. <i>Date of Electronic Publication: </i>2011 Mar 21.
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