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Fully activated MEK1 exhibits compromised affinity for binding of allosteric inhibitors U0126 and PD0325901.

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Title: Fully activated MEK1 exhibits compromised affinity for binding of allosteric inhibitors U0126 and PD0325901.
Authors: Sheth PR; Protein Science Department, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, USA. payal.sheth@merck.com, Liu Y, Hesson T, Zhao J, Vilenchik L, Liu YH, Mayhood TW, Le HV
Source: Biochemistry [Biochemistry] 2011 Sep 20; Vol. 50 (37), pp. 7964-76. Date of Electronic Publication: 2011 Aug 26.
Publication Type: Comparative Study; Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Fully activated MEK1 exhibits compromised affinity for binding of allosteric inhibitors U0126 and PD0325901.
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  Data: <searchLink fieldCode="AU" term="%22Sheth+PR%22">Sheth PR</searchLink>; Protein Science Department, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, USA. payal.sheth@merck.com<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink><br /><searchLink fieldCode="AU" term="%22Hesson+T%22">Hesson T</searchLink><br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink><br /><searchLink fieldCode="AU" term="%22Vilenchik+L%22">Vilenchik L</searchLink><br /><searchLink fieldCode="AU" term="%22Liu+YH%22">Liu YH</searchLink><br /><searchLink fieldCode="AU" term="%22Mayhood+TW%22">Mayhood TW</searchLink><br /><searchLink fieldCode="AU" term="%22Le+HV%22">Le HV</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220370623%22">Biochemistry</searchLink> [Biochemistry] 2011 Sep 20; Vol. 50 (37), pp. 7964-76. <i>Date of Electronic Publication: </i>2011 Aug 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370623 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4995 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200062960%22">00062960 </searchLink><i>NLM ISO Abbreviation: </i>Biochemistry <i>Subsets: </i>MEDLINE
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        Value: 10.1021/bi200542r
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      – Code: eng
        Text: English
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        StartPage: 7964
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      – TitleFull: Fully activated MEK1 exhibits compromised affinity for binding of allosteric inhibitors U0126 and PD0325901.
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              Text: 2011 Sep 20
              Type: published
              Y: 2011
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              Value: 50
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              Value: 37
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            – TitleFull: Biochemistry
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