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Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases.

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Title: Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases.
Authors: Dakin LA; Oncology iMed Sciences Group, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, MA 02451, USA., Block MH, Chen H, Code E, Dowling JE, Feng X, Ferguson AD, Green I, Hird AW, Howard T, Keeton EK, Lamb ML, Lyne PD, Pollard H, Read J, Wu AJ, Zhang T, Zheng X
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2012 Jul 15; Vol. 22 (14), pp. 4599-604. Date of Electronic Publication: 2012 Jun 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases.
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  Data: <searchLink fieldCode="AU" term="%22Dakin+LA%22">Dakin LA</searchLink>; Oncology iMed Sciences Group, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, MA 02451, USA.<br /><searchLink fieldCode="AU" term="%22Block+MH%22">Block MH</searchLink><br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink><br /><searchLink fieldCode="AU" term="%22Code+E%22">Code E</searchLink><br /><searchLink fieldCode="AU" term="%22Dowling+JE%22">Dowling JE</searchLink><br /><searchLink fieldCode="AU" term="%22Feng+X%22">Feng X</searchLink><br /><searchLink fieldCode="AU" term="%22Ferguson+AD%22">Ferguson AD</searchLink><br /><searchLink fieldCode="AU" term="%22Green+I%22">Green I</searchLink><br /><searchLink fieldCode="AU" term="%22Hird+AW%22">Hird AW</searchLink><br /><searchLink fieldCode="AU" term="%22Howard+T%22">Howard T</searchLink><br /><searchLink fieldCode="AU" term="%22Keeton+EK%22">Keeton EK</searchLink><br /><searchLink fieldCode="AU" term="%22Lamb+ML%22">Lamb ML</searchLink><br /><searchLink fieldCode="AU" term="%22Lyne+PD%22">Lyne PD</searchLink><br /><searchLink fieldCode="AU" term="%22Pollard+H%22">Pollard H</searchLink><br /><searchLink fieldCode="AU" term="%22Read+J%22">Read J</searchLink><br /><searchLink fieldCode="AU" term="%22Wu+AJ%22">Wu AJ</searchLink><br /><searchLink fieldCode="AU" term="%22Zhang+T%22">Zhang T</searchLink><br /><searchLink fieldCode="AU" term="%22Zheng+X%22">Zheng X</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2012 Jul 15; Vol. 22 (14), pp. 4599-604. <i>Date of Electronic Publication: </i>2012 Jun 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9107377 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1464-3405 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220960894X%22">0960894X </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem Lett <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bmcl.2012.05.098
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        Text: English
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              Text: 2012 Jul 15
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