Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications.
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| Title: | Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications. |
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| Authors: | Tan B; Translational Science and Technologies, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA., Young DA, Lu ZH, Wang T, Meier TI, Shepard RL, Roth K, Zhai Y, Huss K, Kuo MS, Gillig J, Parthasarathy S, Burkholder TP, Smith MC, Geeganage S, Zhao G |
| Source: | The Journal of biological chemistry [J Biol Chem] 2013 Feb 01; Vol. 288 (5), pp. 3500-11. Date of Electronic Publication: 2012 Dec 13. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 23239881 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tan+B%22">Tan B</searchLink>; Translational Science and Technologies, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA.<br /><searchLink fieldCode="AU" term="%22Young+DA%22">Young DA</searchLink><br /><searchLink fieldCode="AU" term="%22Lu+ZH%22">Lu ZH</searchLink><br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink><br /><searchLink fieldCode="AU" term="%22Meier+TI%22">Meier TI</searchLink><br /><searchLink fieldCode="AU" term="%22Shepard+RL%22">Shepard RL</searchLink><br /><searchLink fieldCode="AU" term="%22Roth+K%22">Roth K</searchLink><br /><searchLink fieldCode="AU" term="%22Zhai+Y%22">Zhai Y</searchLink><br /><searchLink fieldCode="AU" term="%22Huss+K%22">Huss K</searchLink><br /><searchLink fieldCode="AU" term="%22Kuo+MS%22">Kuo MS</searchLink><br /><searchLink fieldCode="AU" term="%22Gillig+J%22">Gillig J</searchLink><br /><searchLink fieldCode="AU" term="%22Parthasarathy+S%22">Parthasarathy S</searchLink><br /><searchLink fieldCode="AU" term="%22Burkholder+TP%22">Burkholder TP</searchLink><br /><searchLink fieldCode="AU" term="%22Smith+MC%22">Smith MC</searchLink><br /><searchLink fieldCode="AU" term="%22Geeganage+S%22">Geeganage S</searchLink><br /><searchLink fieldCode="AU" term="%22Zhao+G%22">Zhao G</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2013 Feb 01; Vol. 288 (5), pp. 3500-11. <i>Date of Electronic Publication: </i>2012 Dec 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985121R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1083-351X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219258%22">00219258 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=23239881 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1074/jbc.M112.394510 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 3500 Titles: – TitleFull: Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tan B – PersonEntity: Name: NameFull: Young DA – PersonEntity: Name: NameFull: Lu ZH – PersonEntity: Name: NameFull: Wang T – PersonEntity: Name: NameFull: Meier TI – PersonEntity: Name: NameFull: Shepard RL – PersonEntity: Name: NameFull: Roth K – PersonEntity: Name: NameFull: Zhai Y – PersonEntity: Name: NameFull: Huss K – PersonEntity: Name: NameFull: Kuo MS – PersonEntity: Name: NameFull: Gillig J – PersonEntity: Name: NameFull: Parthasarathy S – PersonEntity: Name: NameFull: Burkholder TP – PersonEntity: Name: NameFull: Smith MC – PersonEntity: Name: NameFull: Geeganage S – PersonEntity: Name: NameFull: Zhao G IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2013 Feb 01 Type: published Y: 2013 Identifiers: – Type: issn-electronic Value: 1083-351X Numbering: – Type: volume Value: 288 – Type: issue Value: 5 Titles: – TitleFull: The Journal of biological chemistry Type: main |
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