Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna) with the human ABC drug transporter P-glycoprotein.
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| Title: | Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna) with the human ABC drug transporter P-glycoprotein. |
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| Authors: | Shukla S; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Chufan EE; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Singh S; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St John's University, Queens, NY, USA., Skoumbourdis AP; NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, Rockville, MD, USA., Kapoor K; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Boxer MB; NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, Rockville, MD, USA., Duveau DY; NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, Rockville, MD, USA., Thomas CJ; NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, Rockville, MD, USA., Talele TT; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St John's University, Queens, NY, USA., Ambudkar SV; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. |
| Source: | Leukemia [Leukemia] 2014 Apr; Vol. 28 (4), pp. 961-4. Date of Electronic Publication: 2014 Jan 14. |
| Publication Type: | Letter; Research Support, N.I.H., Intramural |
| Journal Info: | Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 24418991 AccessLevel: 2 PubType: Report PubTypeId: report PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna) with the human ABC drug transporter P-glycoprotein. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Shukla+S%22">Shukla S</searchLink>; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chufan+EE%22">Chufan EE</searchLink>; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Singh+S%22">Singh S</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St John's University, Queens, NY, USA.<br /><searchLink fieldCode="AU" term="%22Skoumbourdis+AP%22">Skoumbourdis AP</searchLink>; NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kapoor+K%22">Kapoor K</searchLink>; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Boxer+MB%22">Boxer MB</searchLink>; NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Duveau+DY%22">Duveau DY</searchLink>; NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+CJ%22">Thomas CJ</searchLink>; NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Talele+TT%22">Talele TT</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St John's University, Queens, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ambudkar+SV%22">Ambudkar SV</searchLink>; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2014 Apr; Vol. 28 (4), pp. 961-4. <i>Date of Electronic Publication: </i>2014 Jan 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Letter; Research Support, N.I.H., Intramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%2C+Specialist+Journals%22">Nature Publishing Group, Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8704895 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5551 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208876924%22">08876924 </searchLink><i>NLM ISO Abbreviation: </i>Leukemia <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=24418991 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/leu.2014.21 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 961 Titles: – TitleFull: Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna) with the human ABC drug transporter P-glycoprotein. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Shukla S – PersonEntity: Name: NameFull: Chufan EE – PersonEntity: Name: NameFull: Singh S – PersonEntity: Name: NameFull: Skoumbourdis AP – PersonEntity: Name: NameFull: Kapoor K – PersonEntity: Name: NameFull: Boxer MB – PersonEntity: Name: NameFull: Duveau DY – PersonEntity: Name: NameFull: Thomas CJ – PersonEntity: Name: NameFull: Talele TT – PersonEntity: Name: NameFull: Ambudkar SV IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2014 Apr Type: published Y: 2014 Identifiers: – Type: issn-electronic Value: 1476-5551 Numbering: – Type: volume Value: 28 – Type: issue Value: 4 Titles: – TitleFull: Leukemia Type: main |
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