Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model.
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| Title: | Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model. |
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| Authors: | Wang Z; 1] Program in Transplantation Biology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Medicine, University of Washington, Seattle, WA, USA., Halbert CL; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Lee D; Department of Radiology, University of Washington, Seattle, WA, USA., Butts T; Program in Transplantation Biology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Tapscott SJ; 1] Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Neurology, University of Washington, Seattle, WA, USA., Storb R; 1] Program in Transplantation Biology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Medicine, University of Washington, Seattle, WA, USA., Miller AD; 1] Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Pathology, University of Washington, Seattle, WA, USA. |
| Source: | Gene therapy [Gene Ther] 2014 Apr; Vol. 21 (4), pp. 363-70. Date of Electronic Publication: 2014 Feb 06. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 24500525 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; 1] Program in Transplantation Biology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Halbert+CL%22">Halbert CL</searchLink>; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Lee+D%22">Lee D</searchLink>; Department of Radiology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Butts+T%22">Butts T</searchLink>; Program in Transplantation Biology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Tapscott+SJ%22">Tapscott SJ</searchLink>; 1] Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Neurology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Storb+R%22">Storb R</searchLink>; 1] Program in Transplantation Biology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Miller+AD%22">Miller AD</searchLink>; 1] Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Pathology, University of Washington, Seattle, WA, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229421525%22">Gene therapy</searchLink> [Gene Ther] 2014 Apr; Vol. 21 (4), pp. 363-70. <i>Date of Electronic Publication: </i>2014 Feb 06. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9421525 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5462 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209697128%22">09697128 </searchLink><i>NLM ISO Abbreviation: </i>Gene Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=24500525 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/gt.2014.4 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 363 Titles: – TitleFull: Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang Z – PersonEntity: Name: NameFull: Halbert CL – PersonEntity: Name: NameFull: Lee D – PersonEntity: Name: NameFull: Butts T – PersonEntity: Name: NameFull: Tapscott SJ – PersonEntity: Name: NameFull: Storb R – PersonEntity: Name: NameFull: Miller AD IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2014 Apr Type: published Y: 2014 Identifiers: – Type: issn-electronic Value: 1476-5462 Numbering: – Type: volume Value: 21 – Type: issue Value: 4 Titles: – TitleFull: Gene therapy Type: main |
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