Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model.
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| Title: | Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model. |
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| Authors: | Wang Z; 1] Program in Transplantation Biology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Medicine, University of Washington, Seattle, WA, USA., Halbert CL; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Lee D; Department of Radiology, University of Washington, Seattle, WA, USA., Butts T; Program in Transplantation Biology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Tapscott SJ; 1] Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Neurology, University of Washington, Seattle, WA, USA., Storb R; 1] Program in Transplantation Biology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Medicine, University of Washington, Seattle, WA, USA., Miller AD; 1] Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Pathology, University of Washington, Seattle, WA, USA. |
| Source: | Gene therapy [Gene Ther] 2014 Apr; Vol. 21 (4), pp. 363-70. Date of Electronic Publication: 2014 Feb 06. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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