Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.

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Bibliographic Details
Title: Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.
Authors: Menon S; Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA., Dibble CC; Department of Systems Biology, Harvard Medical School and Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. Electronic address: ccdibble@bidmc.harvard.edu., Talbott G; Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA., Hoxhaj G; Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA., Valvezan AJ; Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA., Takahashi H; Department of Systems Biology, Harvard Medical School and Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA., Cantley LC; Department of Systems Biology, Harvard Medical School and Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA; Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA., Manning BD; Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA. Electronic address: bmanning@hsph.harvard.edu.
Source: Cell [Cell] 2014 Feb 13; Vol. 156 (4), pp. 771-85.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4172
DOI:10.1016/j.cell.2013.11.049