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ST2 deficiency does not impair type 2 immune responses during chronic filarial infection but leads to an increased microfilaremia due to an impaired splenic microfilarial clearance.

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Title: ST2 deficiency does not impair type 2 immune responses during chronic filarial infection but leads to an increased microfilaremia due to an impaired splenic microfilarial clearance.
Authors: Ajendra J; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany., Specht S; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany., Neumann AL; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany., Gondorf F; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany., Schmidt D; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany., Gentil K; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany., Hoffmann WH; Institute of Tropical Medicine, University of Tuebingen, Tuebingen, Germany., Taylor MJ; Filariasis Research Laboratory, Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Hoerauf A; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany., Hübner MP; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
Source: PloS one [PLoS One] 2014 Mar 24; Vol. 9 (3), pp. e93072. Date of Electronic Publication: 2014 Mar 24 (Print Publication: 2014).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0093072