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An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.

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Title: An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
Authors: Seguin L; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Kato S; School of Medicine, Division of Hematology/Oncology, University of California, San Diego, La Jolla, California 92093, USA., Franovic A; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Camargo MF; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Lesperance J; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Elliott KC; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Yebra M; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Mielgo A; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Lowy AM; Division of Surgical Oncology, Departments of Surgery, San Diego, La Jolla, California 92093, USA., Husain H; School of Medicine, Division of Hematology/Oncology, University of California, San Diego, La Jolla, California 92093, USA., Cascone T; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA., Diao L; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA., Wang J; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA., Wistuba II; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA., Heymach JV; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA., Lippman SM; Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Desgrosellier JS; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Anand S; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Weis SM; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Cheresh DA; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.
Source: Nature cell biology [Nat Cell Biol] 2014 May; Vol. 16 (5), pp. 457-68. Date of Electronic Publication: 2014 Apr 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
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  Data: An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Seguin+L%22">Seguin L</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Kato+S%22">Kato S</searchLink>; School of Medicine, Division of Hematology/Oncology, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Franovic+A%22">Franovic A</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Camargo+MF%22">Camargo MF</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Lesperance+J%22">Lesperance J</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Elliott+KC%22">Elliott KC</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Yebra+M%22">Yebra M</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Mielgo+A%22">Mielgo A</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Lowy+AM%22">Lowy AM</searchLink>; Division of Surgical Oncology, Departments of Surgery, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Husain+H%22">Husain H</searchLink>; School of Medicine, Division of Hematology/Oncology, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Cascone+T%22">Cascone T</searchLink>; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA.<br /><searchLink fieldCode="AU" term="%22Diao+L%22">Diao L</searchLink>; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA.<br /><searchLink fieldCode="AU" term="%22Wistuba+II%22">Wistuba II</searchLink>; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA.<br /><searchLink fieldCode="AU" term="%22Heymach+JV%22">Heymach JV</searchLink>; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA.<br /><searchLink fieldCode="AU" term="%22Lippman+SM%22">Lippman SM</searchLink>; Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Desgrosellier+JS%22">Desgrosellier JS</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Anand+S%22">Anand S</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Weis+SM%22">Weis SM</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.<br /><searchLink fieldCode="AU" term="%22Cheresh+DA%22">Cheresh DA</searchLink>; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.
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  Data: <searchLink fieldCode="JN" term="%22100890575%22">Nature cell biology</searchLink> [Nat Cell Biol] 2014 May; Vol. 16 (5), pp. 457-68. <i>Date of Electronic Publication: </i>2014 Apr 20.
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