Why did the FDA approve efavirenz 800 mg when co-administered with rifampin?

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Bibliographic Details
Title: Why did the FDA approve efavirenz 800 mg when co-administered with rifampin?
Authors: Liu J, Chan-Tack KM, Jadhav P, Seo S, Robertson SM, Kraft J, Singer ME, Struble KA, Arya V
Source: International journal of clinical pharmacology and therapeutics [Int J Clin Pharmacol Ther] 2014 Jun; Vol. 52 (6), pp. 446-53.
Publication Type: Journal Article
Journal Info: Publisher: Dustri-Verlag Dr. K. Feistle Country of Publication: Germany NLM ID: 9423309 Publication Model: Print Cited Medium: Print ISSN: 0946-1965 (Print) Linking ISSN: 09461965 NLM ISO Abbreviation: Int J Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:0946-1965
DOI:10.5414/CP202079