Why did the FDA approve efavirenz 800 mg when co-administered with rifampin?

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Title: Why did the FDA approve efavirenz 800 mg when co-administered with rifampin?
Authors: Liu J, Chan-Tack KM, Jadhav P, Seo S, Robertson SM, Kraft J, Singer ME, Struble KA, Arya V
Source: International journal of clinical pharmacology and therapeutics [Int J Clin Pharmacol Ther] 2014 Jun; Vol. 52 (6), pp. 446-53.
Publication Type: Journal Article
Journal Info: Publisher: Dustri-Verlag Dr. K. Feistle Country of Publication: Germany NLM ID: 9423309 Publication Model: Print Cited Medium: Print ISSN: 0946-1965 (Print) Linking ISSN: 09461965 NLM ISO Abbreviation: Int J Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Dustri-Verlag+Dr%2E+K%2E+Feistle%22">Dustri-Verlag Dr. K. Feistle </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9423309 <i>Publication Model: </i>Print <i>Cited Medium: </i>Print <i>ISSN: </i>0946-1965 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209461965%22">09461965 </searchLink><i>NLM ISO Abbreviation: </i>Int J Clin Pharmacol Ther <i>Subsets: </i>MEDLINE
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        Value: 10.5414/CP202079
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        Text: English
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              Text: 2014 Jun
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