Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.
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| Title: | Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis. |
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| Authors: | Roberts BR; Florey Institute of Neuroscience and Mental Health., Lim NK; Department of Pathology., McAllum EJ; Department of Pathology., Donnelly PS; School of Chemistry, Bio21 Institute of Biotechnology and Molecular Biology, and., Hare DJ; Florey Institute of Neuroscience and Mental Health, Elemental Bio-imaging Facility, and Department of Chemistry and Forensic Science, University of Technology Sydney, 2007 Broadway, New South Wales, Australia., Doble PA; Elemental Bio-imaging Facility, and Department of Chemistry and Forensic Science, University of Technology Sydney, 2007 Broadway, New South Wales, Australia., Turner BJ; Florey Institute of Neuroscience and Mental Health., Price KA; Department of Pathology., Lim SC; School of Chemistry, Bio21 Institute of Biotechnology and Molecular Biology, and., Paterson BM; School of Chemistry, Bio21 Institute of Biotechnology and Molecular Biology, and., Hickey JL; School of Chemistry, Bio21 Institute of Biotechnology and Molecular Biology, and., Rhoads TW; Department of Biochemistry and Biophysics, Linus Pauling Institute, and., Williams JR; Department of Biochemistry and Biophysics, Linus Pauling Institute, and., Kanninen KM; Department of Pathology., Hung LW; Florey Institute of Neuroscience and Mental Health, Bio21 Institute of Biotechnology and Molecular Biology, and., Liddell JR; Department of Pathology., Grubman A; Department of Pathology., Monty JF; Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, 3125 Victoria, Australia., Llanos RM; Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, 3125 Victoria, Australia., Kramer DR; ANU Medical School, ANU College of Medicine, Biology and the Environment, The Australian National University, 0200 Canberra, Australian Capital Territory, Australia, and., Mercer JF; Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, 3125 Victoria, Australia., Bush AI; Florey Institute of Neuroscience and Mental Health., Masters CL; Florey Institute of Neuroscience and Mental Health., Duce JA; Florey Institute of Neuroscience and Mental Health, School of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom., Li QX; Florey Institute of Neuroscience and Mental Health., Beckman JS; Department of Biochemistry and Biophysics, Linus Pauling Institute, and Environmental Health Sciences Centre, Oregon State University, Corvallis, Oregon 97331., Barnham KJ; Florey Institute of Neuroscience and Mental Health, Bio21 Institute of Biotechnology and Molecular Biology, and Department of Pharmacology, The University of Melbourne, Parkville, 3010 Victoria, Australia., White AR; Florey Institute of Neuroscience and Mental Health, Department of Pathology., Crouch PJ; Florey Institute of Neuroscience and Mental Health, Department of Pathology, pjcrouch@unimelb.edu.au. |
| Source: | The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2014 Jun 04; Vol. 34 (23), pp. 8021-31. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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