A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment.
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| Title: | A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment. |
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| Authors: | Lee H; Department of Medicine, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA., Brendle SA; Department of Pathology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA., Bywaters SM; Department of Pathology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA., Guan J; Department of Medicine, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA., Ashley RE; Department of Medicine, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA., Yoder JD; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Makhov AM; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Conway JF; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Christensen ND; Department of Pathology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA., Hafenstein S; Department of Medicine, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA shafenstein@hmc.psu.edu. |
| Source: | Journal of virology [J Virol] 2015 Jan 15; Vol. 89 (2), pp. 1428-38. Date of Electronic Publication: 2014 Nov 12. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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