A randomized, double-blind, comparative study to assess the safety and efficacy of topical retapamulin ointment 1% versus oral linezolid in the treatment of secondarily infected traumatic lesions and impetigo due to methicillin-resistant Staphylococcus aureus.

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Title: A randomized, double-blind, comparative study to assess the safety and efficacy of topical retapamulin ointment 1% versus oral linezolid in the treatment of secondarily infected traumatic lesions and impetigo due to methicillin-resistant Staphylococcus aureus.
Authors: Tanus T; Tonny Tanus, MD, is Director, Kern Allergy Medical Clinic Inc, Bakersfield, California, and Assistant Clinical Professor, David Geffen School of Medicine, University of California, Los Angeles. Nicole E. Scangarella-Oman, MS, is an Investigator; Marybeth Dalessandro, BS, is Manager, Clinical Development; Gang Li, PhD, is Manager, Statistics; John J. Breton, MCM, is Manager, Clinical Development; and John F. Tomayko, MD, is Senior Director, all in the Department of Infectious Diseases Medicines Discovery and Development, GlaxoSmithKline, Collegeville, Pennsylvania. The authors disclose they will discuss off-label uses of retapamulin 1% (Altabax, Altargo). Dr Tanus has disclosed that he is/was a recipient of grant/research funding from Stiefel/GlaxoSmithKline, Amgen, and Genentech; he is a recipient of grant/research funding from Teva Pharmaceuticals; and he was a member of the speakers' bureau for Astra Zeneca. The coauthors have disclosed they are employees of GlaxoSmithKline. Ms Scangarella-Oman, Ms Dalessandro, Mr Breton, and Dr Tomayko have disclosed they are stock shareholders of GlaxoSmithKline. The authors disclose that the study was supported by funding from GlaxoSmithKline., Scangarella-Oman NE, Dalessandro M, Li G, Breton JJ, Tomayko JF
Source: Advances in skin & wound care [Adv Skin Wound Care] 2014 Dec; Vol. 27 (12), pp. 548-59.
Publication Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 100911021 Publication Model: Print Cited Medium: Internet ISSN: 1538-8654 (Electronic) Linking ISSN: 15277941 NLM ISO Abbreviation: Adv Skin Wound Care
Database: MEDLINE Ultimate
Description
ISSN:1538-8654
DOI:10.1097/01.ASW.0000456631.20389.ae