Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling.

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Title: Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling.
Authors: Gordts PLSM; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Foley EM; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA 92093, USA., Lawrence R; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Sinha R; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Lameda-Diaz C; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Deng L; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Nock R; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Glass CK; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Erbilgin A; Department of Cardiology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Lusis AJ; Department of Cardiology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Witztum JL; Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Esko JD; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: jesko@ucsd.edu.
Source: Cell metabolism [Cell Metab] 2014 Nov 04; Vol. 20 (5), pp. 813-826. Date of Electronic Publication: 2014 Nov 04.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1932-7420
DOI:10.1016/j.cmet.2014.09.016