Discovery of indole-derived pyridopyrazine-1,6-dione γ-secretase modulators that target presenilin.
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| Title: | Discovery of indole-derived pyridopyrazine-1,6-dione γ-secretase modulators that target presenilin. |
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| Authors: | Pettersson M; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA. Electronic address: martin.pettersson@pfizer.com., Johnson DS; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA., Humphrey JM; Eastern Point Road, Groton, CT 06340, USA., Am Ende CW; Eastern Point Road, Groton, CT 06340, USA., Evrard E; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA., Efremov I; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA., Kauffman GW; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA., Stepan AF; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA., Stiff CM; Eastern Point Road, Groton, CT 06340, USA., Xie L; Eastern Point Road, Groton, CT 06340, USA., Bales KR; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA., Hajos-Korcsok E; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA., Murrey HE; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA., Pustilnik LR; Eastern Point Road, Groton, CT 06340, USA., Steyn SJ; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA., Wood KM; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA., Verhoest PR; Pfizer Worldwide Research & Development, 610 Main Street, Cambridge, MA 02139, USA. |
| Source: | Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2015 Feb 15; Vol. 25 (4), pp. 908-13. Date of Electronic Publication: 2014 Dec 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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