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Monounsaturated fatty acid-enriched high-fat diets impede adipose NLRP3 inflammasome-mediated IL-1β secretion and insulin resistance despite obesity.

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Title: Monounsaturated fatty acid-enriched high-fat diets impede adipose NLRP3 inflammasome-mediated IL-1β secretion and insulin resistance despite obesity.
Authors: Finucane OM; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland., Lyons CL; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland., Murphy AM; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland., Reynolds CM; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland., Klinger R; School of Biomolecular & Biomedical Science, University College Dublin, Belfield, Dublin, Ireland., Healy NP; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland., Cooke AA; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland., Coll RC; Inflammatory Research Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., McAllan L; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland., Nilaweera KN; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland., O'Reilly ME; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland., Tierney AC; Department of Dietetics and Human Nutrition, La Trobe University, Melbourne, Victoria, Australia., Morine MJ; The Microsoft Research-University of Trento Centre for Computational and Systems Biology, Rovereto, Italy., Alcala-Diaz JF; Lipids and Atherosclerosis Research Unit, Reina Sofía University Hospital, and CIBER Phyisiopathology of Obesity and Nutrition (CIBEROBN), University of Córdoba, Córdoba, Spain., Lopez-Miranda J; Lipids and Atherosclerosis Research Unit, Reina Sofía University Hospital, and CIBER Phyisiopathology of Obesity and Nutrition (CIBEROBN), University of Córdoba, Córdoba, Spain., O'Connor DP; School of Biomolecular & Biomedical Science, University College Dublin, Belfield, Dublin, Ireland., O'Neill LA; Inflammatory Research Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., McGillicuddy FC; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland., Roche HM; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland helen.roche@ucd.ie.
Source: Diabetes [Diabetes] 2015 Jun; Vol. 64 (6), pp. 2116-28. Date of Electronic Publication: 2015 Jan 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Monounsaturated fatty acid-enriched high-fat diets impede adipose NLRP3 inflammasome-mediated IL-1β secretion and insulin resistance despite obesity.
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  Data: <searchLink fieldCode="AU" term="%22Finucane+OM%22">Finucane OM</searchLink>; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Lyons+CL%22">Lyons CL</searchLink>; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Murphy+AM%22">Murphy AM</searchLink>; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Reynolds+CM%22">Reynolds CM</searchLink>; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Klinger+R%22">Klinger R</searchLink>; School of Biomolecular & Biomedical Science, University College Dublin, Belfield, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Healy+NP%22">Healy NP</searchLink>; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Cooke+AA%22">Cooke AA</searchLink>; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Coll+RC%22">Coll RC</searchLink>; Inflammatory Research Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22McAllan+L%22">McAllan L</searchLink>; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland.<br /><searchLink fieldCode="AU" term="%22Nilaweera+KN%22">Nilaweera KN</searchLink>; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland.<br /><searchLink fieldCode="AU" term="%22O'Reilly+ME%22">O'Reilly ME</searchLink>; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Tierney+AC%22">Tierney AC</searchLink>; Department of Dietetics and Human Nutrition, La Trobe University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Morine+MJ%22">Morine MJ</searchLink>; The Microsoft Research-University of Trento Centre for Computational and Systems Biology, Rovereto, Italy.<br /><searchLink fieldCode="AU" term="%22Alcala-Diaz+JF%22">Alcala-Diaz JF</searchLink>; Lipids and Atherosclerosis Research Unit, Reina Sofía University Hospital, and CIBER Phyisiopathology of Obesity and Nutrition (CIBEROBN), University of Córdoba, Córdoba, Spain.<br /><searchLink fieldCode="AU" term="%22Lopez-Miranda+J%22">Lopez-Miranda J</searchLink>; Lipids and Atherosclerosis Research Unit, Reina Sofía University Hospital, and CIBER Phyisiopathology of Obesity and Nutrition (CIBEROBN), University of Córdoba, Córdoba, Spain.<br /><searchLink fieldCode="AU" term="%22O'Connor+DP%22">O'Connor DP</searchLink>; School of Biomolecular & Biomedical Science, University College Dublin, Belfield, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22O'Neill+LA%22">O'Neill LA</searchLink>; Inflammatory Research Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22McGillicuddy+FC%22">McGillicuddy FC</searchLink>; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Roche+HM%22">Roche HM</searchLink>; Nutrigenomics Research Group, Conway Institute of Biomedical and Biomolecular Research, and Institute of Food and Health, University College Dublin, Belfield, Dublin, Ireland helen.roche@ucd.ie.
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  Data: <searchLink fieldCode="JN" term="%220372763%22">Diabetes</searchLink> [Diabetes] 2015 Jun; Vol. 64 (6), pp. 2116-28. <i>Date of Electronic Publication: </i>2015 Jan 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Diabetes+Association%22">American Diabetes Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372763 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1939-327X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200121797%22">00121797 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes <i>Subsets: </i>MEDLINE
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