Effect of cleaning agents and additives on Protein A ligand degradation and chromatography performance.
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| Title: | Effect of cleaning agents and additives on Protein A ligand degradation and chromatography performance. |
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| Authors: | Yang L; Manufacturing Sciences, AbbVie Bioresearch Center, Worcester, MA 01605, USA. Electronic address: lihua.yang@abbvie.com., Harding JD; Manufacturing Sciences, AbbVie Bioresearch Center, Worcester, MA 01605, USA. Electronic address: jason.harding@abbvie.com., Ivanov AV; Global Biologics, AbbVie Bioresearch Center, Worcester, MA 01605, USA. Electronic address: ivanov.alexander@abbvie.com., Ramasubramanyan N; Manufacturing Sciences, AbbVie Bioresearch Center, Worcester, MA 01605, USA. Electronic address: natraj.ram@abbvie.com., Dong DD; Manufacturing Sciences, AbbVie Bioresearch Center, Worcester, MA 01605, USA. Electronic address: diane.dong@abbvie.com. |
| Source: | Journal of chromatography. A [J Chromatogr A] 2015 Mar 13; Vol. 1385, pp. 63-8. Date of Electronic Publication: 2015 Jan 31. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3778 (Electronic) Linking ISSN: 00219673 NLM ISO Abbreviation: J Chromatogr A Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1873-3778 |
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| DOI: | 10.1016/j.chroma.2015.01.068 |