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A phase 2 study of the BH3 mimetic BCL2 inhibitor navitoclax (ABT-263) with or without rituximab, in previously untreated B-cell chronic lymphocytic leukemia.

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Title: A phase 2 study of the BH3 mimetic BCL2 inhibitor navitoclax (ABT-263) with or without rituximab, in previously untreated B-cell chronic lymphocytic leukemia.
Authors: Kipps TJ; a Department of Hematology-Oncology , UCSD School of Medicine , San Diego , CA , USA., Eradat H; b Division of Hematology-Oncology, David Geffen School of Medicine at UCLA , Los Angeles , CA , USA., Grosicki S; c Department of Hematology , Community Hospitals , Chorzow , Poland., Catalano J; d Frankston Hospital and Monash University , Frankston , Australia., Cosolo W; e John Fawkner Cancer Trial Centre , Coburg , Australia., Dyagil IS; f Department of Hematology , National Research Center for Radiation Medicine of National Medical Academy of Sciences of Ukraine , Kyiv , Ukraine., Yalamanchili S; g Genentech, Inc. , South San Francisco , CA , USA., Chai A; g Genentech, Inc. , South San Francisco , CA , USA., Sahasranaman S; g Genentech, Inc. , South San Francisco , CA , USA., Punnoose E; g Genentech, Inc. , South San Francisco , CA , USA., Hurst D; g Genentech, Inc. , South San Francisco , CA , USA., Pylypenko H; h Department of Hematology , Cherkassy Regional Oncological Center , Cherkassy , Ukraine.
Source: Leukemia & lymphoma [Leuk Lymphoma] 2015; Vol. 56 (10), pp. 2826-33. Date of Electronic Publication: 2015 May 12.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1029-2403 (Electronic) Linking ISSN: 10268022 NLM ISO Abbreviation: Leuk Lymphoma Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A phase 2 study of the BH3 mimetic BCL2 inhibitor navitoclax (ABT-263) with or without rituximab, in previously untreated B-cell chronic lymphocytic leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Kipps+TJ%22">Kipps TJ</searchLink>; a Department of Hematology-Oncology , UCSD School of Medicine , San Diego , CA , USA.<br /><searchLink fieldCode="AU" term="%22Eradat+H%22">Eradat H</searchLink>; b Division of Hematology-Oncology, David Geffen School of Medicine at UCLA , Los Angeles , CA , USA.<br /><searchLink fieldCode="AU" term="%22Grosicki+S%22">Grosicki S</searchLink>; c Department of Hematology , Community Hospitals , Chorzow , Poland.<br /><searchLink fieldCode="AU" term="%22Catalano+J%22">Catalano J</searchLink>; d Frankston Hospital and Monash University , Frankston , Australia.<br /><searchLink fieldCode="AU" term="%22Cosolo+W%22">Cosolo W</searchLink>; e John Fawkner Cancer Trial Centre , Coburg , Australia.<br /><searchLink fieldCode="AU" term="%22Dyagil+IS%22">Dyagil IS</searchLink>; f Department of Hematology , National Research Center for Radiation Medicine of National Medical Academy of Sciences of Ukraine , Kyiv , Ukraine.<br /><searchLink fieldCode="AU" term="%22Yalamanchili+S%22">Yalamanchili S</searchLink>; g Genentech, Inc. , South San Francisco , CA , USA.<br /><searchLink fieldCode="AU" term="%22Chai+A%22">Chai A</searchLink>; g Genentech, Inc. , South San Francisco , CA , USA.<br /><searchLink fieldCode="AU" term="%22Sahasranaman+S%22">Sahasranaman S</searchLink>; g Genentech, Inc. , South San Francisco , CA , USA.<br /><searchLink fieldCode="AU" term="%22Punnoose+E%22">Punnoose E</searchLink>; g Genentech, Inc. , South San Francisco , CA , USA.<br /><searchLink fieldCode="AU" term="%22Hurst+D%22">Hurst D</searchLink>; g Genentech, Inc. , South San Francisco , CA , USA.<br /><searchLink fieldCode="AU" term="%22Pylypenko+H%22">Pylypenko H</searchLink>; h Department of Hematology , Cherkassy Regional Oncological Center , Cherkassy , Ukraine.
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  Data: <searchLink fieldCode="JN" term="%229007422%22">Leukemia & lymphoma</searchLink> [Leuk Lymphoma] 2015; Vol. 56 (10), pp. 2826-33. <i>Date of Electronic Publication: </i>2015 May 12.
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  Data: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9007422 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1029-2403 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210268022%22">10268022 </searchLink><i>NLM ISO Abbreviation: </i>Leuk Lymphoma <i>Subsets: </i>MEDLINE
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        Value: 10.3109/10428194.2015.1030638
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