Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics.

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Title: Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics.
Authors: Neller MA; Human Immunity Laboratory, Cellular Immunology Laboratory and Tumour Immunology Laboratory, Queensland Institute of Medical Research, Brisbane, QLD, Australia., Ladell K; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., McLaren JE; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Matthews KK; Human Immunity Laboratory, Cellular Immunology Laboratory and Tumour Immunology Laboratory, Queensland Institute of Medical Research, Brisbane, QLD, Australia., Gostick E; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Pentier JM; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Dolton G; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Schauenburg AJ; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Koning D; Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Fontaine Costa AI; Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Watkins TS; Human Immunity Laboratory, Cellular Immunology Laboratory and Tumour Immunology Laboratory, Queensland Institute of Medical Research, Brisbane, QLD, Australia., Venturi V; Computational Biology Unit, Centre for Vascular Research, University of New South Wales, Kensington, NSW, Australia., Smith C; Human Immunity Laboratory, Cellular Immunology Laboratory and Tumour Immunology Laboratory, Queensland Institute of Medical Research, Brisbane, QLD, Australia., Khanna R; Human Immunity Laboratory, Cellular Immunology Laboratory and Tumour Immunology Laboratory, Queensland Institute of Medical Research, Brisbane, QLD, Australia., Miners K; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Clement M; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Wooldridge L; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Cole DK; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., van Baarle D; Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Sewell AK; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Burrows SR; 1] Human Immunity Laboratory, Cellular Immunology Laboratory and Tumour Immunology Laboratory, Queensland Institute of Medical Research, Brisbane, QLD, Australia [2] School of Medicine, The University of Queensland, Brisbane, QLD, Australia., Price DA; 1] Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK [2] Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Miles JJ; 1] Human Immunity Laboratory, Cellular Immunology Laboratory and Tumour Immunology Laboratory, Queensland Institute of Medical Research, Brisbane, QLD, Australia [2] Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK [3] School of Medicine, The University of Queensland, Brisbane, QLD, Australia.
Source: Immunology and cell biology [Immunol Cell Biol] 2015 Aug; Vol. 93 (7), pp. 625-33. Date of Electronic Publication: 2015 Mar 24.
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 8706300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1440-1711 (Electronic) Linking ISSN: 08189641 NLM ISO Abbreviation: Immunol Cell Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1440-1711
DOI:10.1038/icb.2015.17