Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
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| Title: | Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. |
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| Authors: | Ilkow CS; 1] Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [2] Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada., Marguerie M; 1] Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [2] Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada., Batenchuk C; 1] Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [2] Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada., Mayer J; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Ben Neriah D; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Cousineau S; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Falls T; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Jennings VA; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Boileau M; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Bellamy D; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Bastin D; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., de Souza CT; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Alkayyal A; 1] Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [2] Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia., Zhang J; 1] Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [2] Department of Neurosurgery, the Second Hospital of Shandong University, Jinan, Shandong, China., Le Boeuf F; 1] Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [2] Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada., Arulanandam R; 1] Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [2] Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada., Stubbert L; 1] Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [2] Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada., Sampath P; 1] University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. [2] Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. [3] Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Thorne SH; 1] University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. [2] Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. [3] Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Paramanthan P; The Ottawa Hospital, Division of Gastroenterology, Ottawa, Ontario, Canada., Chatterjee A; The Ottawa Hospital, Division of Gastroenterology, Ottawa, Ontario, Canada., Strieter RM; Global Translational Medicine, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, USA., Burdick M; Department of Medicine, Pulmonary and Critical Care, University of Virginia, Charlottesville, Virginia, USA., Addison CL; 1] Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [2] Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada., Stojdl DF; 1] Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada. [2] Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada., Atkins HL; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Auer RC; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Diallo JS; Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Lichty BD; McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada., Bell JC; 1] Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [2] Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada. |
| Source: | Nature medicine [Nat Med] 2015 May; Vol. 21 (5), pp. 530-6. Date of Electronic Publication: 2015 Apr 20. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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