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Peptide to Peptoid Substitutions Increase Cell Permeability in Cyclic Hexapeptides.

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Title: Peptide to Peptoid Substitutions Increase Cell Permeability in Cyclic Hexapeptides.
Authors: Schwochert J; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States., Turner R; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States., Thang M; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States., Berkeley RF; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States., Ponkey AR; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States., Rodriguez KM; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States., Leung SS; ‡Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States., Khunte B; ∥World Wide Medicinal Chemistry, Groton Laboratories, Pfizer Inc. Groton, Connecticut 06340, United States., Goetz G; ∥World Wide Medicinal Chemistry, Groton Laboratories, Pfizer Inc. Groton, Connecticut 06340, United States., Limberakis C; ∥World Wide Medicinal Chemistry, Groton Laboratories, Pfizer Inc. Groton, Connecticut 06340, United States., Kalgutkar AS; §Pharmacokinetics and Drug Metabolism, Cambridge Laboratories, Pfizer Inc. Cambridge, Massachusetts 02139, United States., Eng H; ⊥Pharmacokinetics and Drug Metabolism, Groton Laboratories, Pfizer Inc. Groton, Connecticut 06340, United States., Shapiro MJ; ∥World Wide Medicinal Chemistry, Groton Laboratories, Pfizer Inc. Groton, Connecticut 06340, United States., Mathiowetz AM; ○World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. Cambridge, Massachusetts 02139, United States., Price DA; ○World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. Cambridge, Massachusetts 02139, United States., Liras S; ○World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. Cambridge, Massachusetts 02139, United States., Jacobson MP; ‡Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States., Lokey RS; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States.
Source: Organic letters [Org Lett] 2015 Jun 19; Vol. 17 (12), pp. 2928-31. Date of Electronic Publication: 2015 Jun 05.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE
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  Data: Peptide to Peptoid Substitutions Increase Cell Permeability in Cyclic Hexapeptides.
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  Data: <searchLink fieldCode="AU" term="%22Schwochert+J%22">Schwochert J</searchLink>; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Turner+R%22">Turner R</searchLink>; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Thang+M%22">Thang M</searchLink>; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Berkeley+RF%22">Berkeley RF</searchLink>; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Ponkey+AR%22">Ponkey AR</searchLink>; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Rodriguez+KM%22">Rodriguez KM</searchLink>; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Leung+SS%22">Leung SS</searchLink>; ‡Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Khunte+B%22">Khunte B</searchLink>; ∥World Wide Medicinal Chemistry, Groton Laboratories, Pfizer Inc. Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Goetz+G%22">Goetz G</searchLink>; ∥World Wide Medicinal Chemistry, Groton Laboratories, Pfizer Inc. Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Limberakis+C%22">Limberakis C</searchLink>; ∥World Wide Medicinal Chemistry, Groton Laboratories, Pfizer Inc. Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Kalgutkar+AS%22">Kalgutkar AS</searchLink>; §Pharmacokinetics and Drug Metabolism, Cambridge Laboratories, Pfizer Inc. Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Eng+H%22">Eng H</searchLink>; ⊥Pharmacokinetics and Drug Metabolism, Groton Laboratories, Pfizer Inc. Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Shapiro+MJ%22">Shapiro MJ</searchLink>; ∥World Wide Medicinal Chemistry, Groton Laboratories, Pfizer Inc. Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Mathiowetz+AM%22">Mathiowetz AM</searchLink>; ○World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Price+DA%22">Price DA</searchLink>; ○World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Liras+S%22">Liras S</searchLink>; ○World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Jacobson+MP%22">Jacobson MP</searchLink>; ‡Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Lokey+RS%22">Lokey RS</searchLink>; †Chemistry and Biochemistry University of California, Santa Cruz, California 95064, United States.
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  Data: <searchLink fieldCode="JN" term="%22100890393%22">Organic letters</searchLink> [Org Lett] 2015 Jun 19; Vol. 17 (12), pp. 2928-31. <i>Date of Electronic Publication: </i>2015 Jun 05.
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        Value: 10.1021/acs.orglett.5b01162
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